FCGR2A gene

Known as: CD32, CD32A, FCG2 
This gene is involved in the regulation of host immune responses and phagocytosis.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Kawasaki disease is a systemic vasculitis of unknown etiology, with clinical observations suggesting a substantial genetic… (More)
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2010
2010
Polymorphisms of activating Fc-γ receptors (FCGRs) on natural killer cells and macrophages result in variable affinity for… (More)
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2010
2010
Anti-CD40L immunotherapy in systemic lupus erythematosus patients was associated with thromboembolism of unknown cause. We… (More)
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Highly Cited
2009
Highly Cited
2009
Human Fcgamma receptors (FcgammaRs) are glycoproteins that bind the Fc region of IgG. The genes encoding the low-affinity… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment with Bevacizumab has been associated with arterial thromboembolism in colorectal cancer patients. However… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Cetuximab, a chimeric immunoglobulin G 1 (IgG1) anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb… (More)
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Highly Cited
2006
Highly Cited
2006
The precise mechanism of rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone (R-CHOP) therapy in diffuse large B… (More)
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2006
2006
The Fc gamma receptors have been shown to play important roles in the initiation and regulation of many immunological and… (More)
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2006
2006
PURPOSE Anti-GD2 murine IgG3 antibody 3F8 kills neuroblastoma cells by antibody-dependent cell-mediated cytotoxicity (ADCC… (More)
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2005
2005
The in vivo mechanism of action of alemtuzumab (anti-CD52; Campath-1H) remains unclear. With rituximab, FCGR3A and FCGR2A high… (More)
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