FAQ

FBXW4 gene

Known as: DACTYLIN, F-box and WD repeat domain containing 4, SHFM3, FORMERLY 
This gene plays a role in both protein turnover and embryonic limb development.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
02419992017

Related topics

Related topics

5 relations
F-Box/WD Repeat-Containing Protein 4Limb DevelopmentProtein Degradation, MetabolicSPLIT-HAND/FOOT MALFORMATION 3

Narrower (1)

FBXW4 wt Allele

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
FBXW4 gene
Limb Development
FBXW4 wt Allele
Protein Degradation, Metabolic
SPLIT-HAND/FOOT MALFORMATION 3
F-Box/WD Repeat-Containing Protein 4

Papers overview

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2017
2017
Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays.
OBJECTIVE To determine the genomic signatures of human uterine leiomyomas and prevalence of MED12 mutations in human uterine… (More)
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2013
2013
The Novel Ubiquitin Ligase Complex, SCFFbxw4, Interacts with the COP9 Signalosome in an F-Box Dependent Manner, Is Mutated, Lost and Under-Expressed in Human Cancers
Identification of novel proteins that can potentially contribute to carcinogenesis is a requisite venture. Herein, we report the… (More)
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2012
2012
Discontinuous microduplications at chromosome 10q24.31 identified in a Chinese family with split hand and foot malformation
Split hand/foot malformation (SHFM) is a congenital disorder characterized by a cleft of the hands and/or feet due to dificiency… (More)
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2007
2007
Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype.
Dactylaplasia, characterized by missing central digital rays, is an inherited mouse limb malformation that depends on two genetic… (More)
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2005
2005
Genomic rearrangement at 10q24 in non-syndromic split-hand/split-foot malformation
Split-hand/split-foot malformation (SHFM) is a congenital limb malformation characterized by a median cleft of hand and/or foot… (More)
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2005
2005
Cliii. a Polysaccharide from the Pollen of Timothy
RECENT investigations of the relationship of various constituents of pollens to the allergic diseases for which they are… (More)
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2003
2003
A genomic rearrangement resulting in a tandem duplication is associated with split hand-split foot malformation 3 (SHFM3) at 10q24.
Split hand-split foot malformation (SHFM) is characterized by hypoplasia/aplasia of the central digits with fusion of the… (More)
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2003
2003
Split hand foot malformation is associated with a reduced level of Dactylin gene expression.
Split hand foot malformation (SHFM) is a congenital limb malformation presenting with a median cleft of the hand and/or foot… (More)
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2000
2000
Genomic organization, chromosomal assignment, and expression analysis of the mouse Suppressor of fused gene (Sufu) coding a Gli protein partner
Suppressor of fused (Sufu) is a negative regulator of the Hedgehog pathway both in Drosophila and vertebrates. Here, we report… (More)
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1999
1999
A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant
Early outgrowth of the vertebrate embryonic limb requires signalling by the apical ectodermal ridge (AER) to the progress zone… (More)
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