FANG vaccine

Known as: bi-shRNA-Furin and Granulocyte Macrophage Colony Stimulating Factor Augmented Autologous Tumor Cell Vaccine, bi-shRNA-Furin/GM-CSF-Expressing Autologous Tumor Cell Vaccine, bi-shRNAi(furin) GMCSF DNA autologous tumor cell vaccine 
Autologous tumor cells transfected with a plasmid expressing recombinant human granulocyte macrophage-colony stimulating factor (rhGM-CSF) and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
We report the weakly interacting massive particle (WIMP) dark matter search results using the first physics-run data of the… (More)
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Highly Cited
2014
Highly Cited
2014
The histone demethylase LSD1 (KDM1A) demethylates mono- and di-methylated (Me2) lysine (K) 4 on histone H3. High LSD1 expression… (More)
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2012
2012
We performed a phase I trial of FANG vaccine, an autologous tumor-based product incorporating a plasmid encoding granulocyte… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Several sirtuin family members (SIRT1-7), which are evolutionarily conserved NAD-dependent deacetylases, play an… (More)
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Highly Cited
2008
Highly Cited
2008
Programmed cell death 4 (Pdcd4) is a tumor suppressor that inhibits neoplastic transformation and tumor invasion. Tissue… (More)
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Highly Cited
2007
Highly Cited
2007
The scaffolding protein WAVE-1 (Wiskott-Aldrich syndrome protein family member 1) directs signals from the GTPase Rac through the… (More)
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Highly Cited
2007
Highly Cited
2007
The formin-homology protein Dia1 is a target of RhoA and a potent activator of nucleation and elongation of actin filaments. Here… (More)
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Highly Cited
2006
Highly Cited
2006
Prion diseases are fatal neurodegenerative diseases characterized by the accumulation of PrP(Sc), the infectious and protease… (More)
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Highly Cited
2002
Highly Cited
2002
In virus-infected cells, the envelope glycoprotein (Env) precursor, gp160, of human immunodeficiency virus type 1 is cleaved by… (More)
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Highly Cited
2000
Highly Cited
2000
The ubiquitous serine endoprotease furin has been implicated in the activation of bacterial toxins and viral glycoproteins as… (More)
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