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FANCL gene
Known as:
Fanconi Anemia, Complementation Group L Gene
, Pog
, FAAP43
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This gene is involved in the mediation of protein ubiquitination.
National Institutes of Health
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Related topics
Related topics
7 relations
Cell Cycle Control
DNA Repair
DNA stability
Fanconi Anemia
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FANCL wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Fanconi Anemia Proteins Function in Mitophagy and Immunity
R. Sumpter
,
Shyam Sirasanagandla
,
+9 authors
B. Levine
Cell
2016
Corpus ID: 26677111
Highly Cited
2015
Highly Cited
2015
Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.
K. Rickman
,
Francis P Lach
,
+10 authors
A. Smogorzewska
Cell reports
2015
Corpus ID: 37449518
Highly Cited
2014
Highly Cited
2014
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
R. Anney
,
A. Avbersek
,
+109 authors
F. Zimprich
The Lancet Neurology
2014
Corpus ID: 3500927
Highly Cited
2014
Highly Cited
2014
The Genetic and Biochemical Basis of FANCD2 Monoubiquitination
E. Rajendra
,
V. Oestergaard
,
+4 authors
L. Passmore
Molecular cell
2014
Corpus ID: 215779575
Highly Cited
2010
Highly Cited
2010
Sex Reversal in Zebrafish fancl Mutants Is Caused by Tp53-Mediated Germ Cell Apoptosis
A. Rodríguez-Marí
,
C. Cañestro
,
+4 authors
J. Postlethwait
PLoS genetics
2010
Corpus ID: 5765186
The molecular genetic mechanisms of sex determination are not known for most vertebrates, including zebrafish. We identified a…
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Highly Cited
2008
Highly Cited
2008
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.
A. Alpi
,
P. Pace
,
M. Babu
,
K. J. Patel
Molecular cell
2008
Corpus ID: 206977126
Highly Cited
2006
Highly Cited
2006
UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation.
Y. Machida
,
Yuka Machida
,
+4 authors
Anindya Dutta
Molecular cell
2006
Corpus ID: 22104093
Highly Cited
2005
Highly Cited
2005
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
O. Levran
,
C. Attwooll
,
+12 authors
A. Auerbach
Nature Genetics
2005
Corpus ID: 32915616
Seven Fanconi anemia–associated proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG and FANCL) form a nuclear Fanconi anemia core…
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Highly Cited
2004
Highly Cited
2004
FANCL Replaces BRCA1 as the Likely Ubiquitin Ligase Responsible for FANCD2 Monoubiquitination
A. R. Meetei
,
Zhijiang Yan
,
Weidong Wang
Cell cycle
2004
Corpus ID: 45723254
Monoubiquitination of FANCD2 is a key step in the DNA damage response pathway involving Fanconi anemia proteins and the breast…
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Highly Cited
2003
Highly Cited
2003
A novel ubiquitin ligase is deficient in Fanconi anemia
A. R. Meetei
,
J. Winter
,
+10 authors
Weidong Wang
Nature Genetics
2003
Corpus ID: 10149290
Fanconi anemia is a recessively inherited disease characterized by congenital defects, bone marrow failure and cancer…
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