FANCL gene

Known as: Fanconi Anemia, Complementation Group L Gene, Pog, FAAP43 
This gene is involved in the mediation of protein ubiquitination.
National Institutes of Health

Papers overview

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2014
2014
The combination of an E2 ubiquitin-conjugating enzyme with an E3 ubiquitin-ligase is essential for ubiquitin modification of a… (More)
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2010
Highly Cited
2010
The molecular genetic mechanisms of sex determination are not known for most vertebrates, including zebrafish. We identified a… (More)
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2010
2010
The Fanconi anemia (FA) pathway is activated in response to DNA damage, leading to monoubiquitination of the substrates FANCI and… (More)
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2009
2009
FANCI is integral to the Fanconi anemia (FA) pathway of DNA damage repair. Upon the occurrence of DNA damage, FANCI becomes… (More)
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Highly Cited
2008
Highly Cited
2008
A key step in the Fanconi anemia (FA) tumor suppressor pathway is the site-specific monoubiquitination of the FANCD2 protein… (More)
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2007
2007
The rare hereditary disorder Fanconi anemia (FA) can be caused by mutations in components of the FA core complex (FancA/B/C/E/F/G… (More)
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2006
2006
Fanconi anemia (FA) is an autosomal recessive disorder characterized by aplastic anemia, cancer susceptibility, and cellular… (More)
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2005
Highly Cited
2005
Seven Fanconi anemia–associated proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG and FANCL) form a nuclear Fanconi anemia core… (More)
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2004
Highly Cited
2004
Monoubiquitination of FANCD2 is a key step in the DNA damage response pathway involving Fanconi anemia proteins and the breast… (More)
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2003
Highly Cited
2003
Fanconi anemia is a recessively inherited disease characterized by congenital defects, bone marrow failure and cancer… (More)
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