F10 wt Allele

Known as: Coagulation Factor X wt Allele, FX, FXA 
The F10 wt Allele is located in the vicinity of 13q34 and is approximately 27 kb in length. This allele, which encodes coagulation factor X protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Inhibitors of coagulation factor Xa (fXa) have emerged as a new class of antithrombotics but lack effective antidotes for… (More)
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Highly Cited
2010
Highly Cited
2010
The complement system as well as the coagulation system has fundamental clinical implications in the context of life-threatening… (More)
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Highly Cited
2010
Highly Cited
2010
Apixaban and other factor Xa (FXa) inhibitors are in late-stage clinical development for prevention and treatment of… (More)
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Highly Cited
2009
Highly Cited
2009
Uncontrolled activation of the coagulation cascade contributes to the pathophysiology of several conditions, including acute and… (More)
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Highly Cited
2007
Highly Cited
2007
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to… (More)
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Review
2007
Review
2007
  • Jack Ansell
  • Journal of thrombosis and haemostasis : JTH
  • 2007
Existing vitamin K antagonists (VKAs) have drawbacks that limit their effectiveness, safety, and overall frequency of use. Oral… (More)
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Review
2003
Review
2003
Our cell-based model of haemostasis replaces the traditional 'cascade' hypothesis, and proposes that coagulation takes place on… (More)
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Highly Cited
2000
Highly Cited
2000
Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and… (More)
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Highly Cited
1999
Highly Cited
1999
Intracellular signaling induced by the coagulation factors (F) VIIa and Xa is poorly understood. We report here studies on these… (More)
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