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Ethylmaleimide

Known as: N-Ethylmaleimide, 1H-Pyrrole-2,5-dione, 1-ethyl-, Ethylmaleimide [Chemical/Ingredient] 
A sulfhydryl reagent that is widely used in experimental biochemical studies.
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

Enzyme InhibitorsMaleimidesSulfhydryl Reagents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

N-ethylmaleimide-gamma-glutamyl-cysteinyl-glycine

Papers overview

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Highly Cited
1984
Highly Cited
1984
Activation by N-ethylmaleimide of a latent K+-Cl- flux in human red blood cells.
Twenty to fifty percent of the ouabain-insensitive Na+ and K+ fluxes in human red blood cells are mediated by Cl(-) -dependent… 
1984
1984
Localization of the N-ethylmaleimide reactive cysteine in the beef heart mitochondrial ADP/ATP carrier protein.
Alkylation of the ADP/ATP carrier protein in beef heart mitochondria by N-ethylmaleimide (NEM) results in inactivation of… 
1983
1983
Structure of the Insulin Receptor of Rat Adipocytes: The Three Interconvertible Redox Forms
Isolated intact rat adipocytes were photoaffinity labeled with radioactive and photoreactive NαB1-monoazi-dobenzoyl insulin (B1… 
Highly Cited
1980
Highly Cited
1980
Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide.
The regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide (NEM) was investigated using the… 
1980
1980
Selective modification of functionally distinct sulfhydryl groups of sarcoplasmic reticulum Ca2+,Mg2+-adenosine triphosphatase with N-ethylmaleimide.
Rabbit sarcoplasmic reticulum vesicles were treated with N-ethylmaleimide (NEM) at pH 7.0. At 1.5 mM NEM, only 4 SH groups per… 
1980
1980
Subcellular distribution and some properties of N-ethylmaleimide-sensitive and-insensitive forms of glycerol phosphate acyltransferase in rat adipocytes.
1. Glycerol phosphate acyltransferase (GPAT) activities were measured in subcellular fractions obtained from rat epididymal… 
1979
1979
Studies on the RNA and protein binding sites of the E. coli ribosomal protein L10.
We have used modification of specific amino acid residues in the E. coli ribosomal protein L10 as a tool to study its… 
Highly Cited
1973
Highly Cited
1973
Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. I. Isolation, subunits, amino acid composition, sulfhydryl groups, and identification of a lysine residue…
Abstract 1. An improved procedure, utilizing affinity chromatography in the final step, has been devised for the purification of… 
1972
1972
Radiation sensitization reactions of N-ethylmaleimide with model compounds.
The reaction of $e_{{\rm aq}}^{-}$ , OH radicals and H atoms with N-ethylmaleimide (NEM) and N-ethylmaleamic acid (NEMA, which is… 
Highly Cited
1960
Highly Cited
1960
Sensitization of Escherichia coli to Gamma-Radiation by N-Ethylmaleimide
WITH the exception of oxygen and nitric oxide, chemical agents which enhance the effect of radiation on bacteria have received…