Ethylketocyclazocine

Known as: 2,6-Methano-3-benzazocin-1(2H)-one, 3-(cyclopropylmethyl)-6-ethyl-3,4,5,6-tetrahydro-8-hydroxy-11-methyl-, (2alpha,6alpha,11S*)-(+-)-, Ethylketazocine, Ethylketocyclazocine [Chemical/Ingredient] 
A kappa opioid receptor agonist. The compound has analgesic action and shows positive inotropic effects on the electrically stimulated left atrium… (More)
National Institutes of Health

Papers overview

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2001
2001
A number of investigators have shown that male animals are more sensitive than females to the antinociceptive effects of mu… (More)
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1988
1988
The objective of this study was to describe, quantitate and compare naloxone-induced abstinence syndromes in rats infused… (More)
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1987
1987
Systemic administration of beta-funaltrexamine (beta-FNA) 24 hr before analgesic testing produced approximately a 10-fold… (More)
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Highly Cited
1985
Highly Cited
1985
The reinforcing properties of various opioid agonists acting preferentially on the kappa and mu opioid receptors were assessed… (More)
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Highly Cited
1983
Highly Cited
1983
A total 31 psychoactive drugs were offered to groups of naive rats for IV self-administration and an injection rate greater than… (More)
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1983
1983
The effects of various opioids (mu agonists, kappa agonists and mixed agonists/antagonists) were determined on urination in the… (More)
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Highly Cited
1983
Highly Cited
1983
U-50,488 (trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide) displays analgesic actions in a variety… (More)
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Highly Cited
1982
Highly Cited
1982
In the guinea pig ileum myenteric plexus--longitudinal muscle preparation, dynorphin-(1--13) and the prototypical kappa agonist… (More)
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1981
1981
Rhesus monkeys lever-pressed under a fixed-ratio 30 time-out 600 sec schedule of i.v. injection of codeine (0.32 mg/kg/injection… (More)
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1980
1980
1 To investigate the opiate receptors that mediate antinociception, the activity profiles of opioid analgesic drugs have been… (More)
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