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Two experiments were conducted to determine the luteotropin of pregnancy in sheep and to examine autocrine and paracrine roles of… Expand Cardiovascular disease and osteoporosis are major causes of illness and death in postmenopausal women. Several observational… Expand This paper describes the laboratory discovery and clinical testing of the first nonsteroidal antiestrogen, MER-25… Expand We determined whether the reduction in placental progesterone (P4) production observed after administration of the antiestrogen… Expand The present study determined if the decline in placental progesterone (P4) production that results from administration of the… Expand Experiments were conducted to determine why tamoxifen, a non-steroidal antiestrogen, is uterotrophic in mice, whereas MER-25… Expand The present study determined whether estrogen is important in the production of progesterone (P) during primate pregnancy. Serum… Expand Two-day-old female rats were given bilateral implants of small pellets each containing 5μg MER-25 in bone wax in the medial… Expand Virgin rats were ovariectomized and tested for induction of maternal behavior by being housed with neonatal young. A… Expand Certain antiuterotrophic agents, such as ethamoxytriphetol, nafoxidine, clomiphene and Parke-Davis CI-628, act by preventing the… Expand