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Ethacrynate Sodium

Known as: Ethacrynic Acid, Sodium Salt, Sodium, Ethacrynate, Sodium Ethacrynate 
The sodium salt form of ethacrynic acid, an unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the… Expand
National Institutes of Health

Related topics

Related topics

17 relations
AnuriaCongestive heart failureDecreased Blood Pressure [PE]Dehydration
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Narrower (1)

Edecrin

Broader (2)

EthacrynateEthacrynic Acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Quality by design in formulation and process development for a freeze-dried, small molecule parenteral product: a case study
A case study has been developed to illustrate one way of incorporating a Quality by Design approach into formulation and process… Expand
2010
2010
The impact of thermal treatment on the stability of freeze dried amorphous pharmaceuticals: I. Dimer formation in sodium ethacrynate.
The objective of this study was to investigate the impact of heat treatment (annealing) on the molecular mobility and chemical… Expand
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Highly Cited
2006
Highly Cited
2006
Coupling Between Chemical Reactivity and Structural Relaxation in Pharmaceutical Glasses
PurposeTo test the hypothesis that the molecular motions associated with chemical degradation in glassy amorphous systems are… Expand
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2004
2004
Effect of cardiac glycosides and sodium ethacrynate on transepithelial sodium transport inin vivo micropuncture experiments and on isolated plasma membrane Na−K ATPasein vitro of the rat
SummaryIn parallel micropuncture experiments employing peritubular capillary perfusion techniquesin vivo and biochemical… Expand
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2001
2001
Stability of ethacrynate sodium after reconstitution in 0.9% sodium chloride injection and storage in polypropylene syringes for pediatric use.
  • J. Ling, V. Gupta
  • International journal of pharmaceutical…
  • 2001
    • Corpus ID: 20729081
The stability of ethacrynate sodium (1 mg/mL) in 0.9% sodium chloride injection has been studied at 25 deg C and 5 deg C in… Expand
1995
1995
The upregulation of Na+,K(+)-ATPase pump numbers in lymphocytes from the first-degree unaffected relatives of patients with manic depressive psychosis in response to in vitro lithium and sodium…
Patients with manic depressive disorder (DSM-III-R bipolar disorder) have an abnormality of the Na+,K(+)-ATPase pumps in their… Expand
1982
1982
Effects of indomethacin, acetazolamide, ethacrynate sodium, and atropine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in pig jejunum.
  • F. Ahrens, B. Zhu
  • Canadian journal of physiology and pharmacology
  • 1982
    • Corpus ID: 42906060
Intraluminal perfusion of pig jejunum with Escherichia coli heat-stable enterotoxin reversed net absorption of water and… Expand
1975
1975
Comparison of the cochlear toxicity of sodium ethacrynate, furosemide, and the cysteine adduct of sodium ethacrynate in cats.
  • R. D. Brown
  • Toxicology and applied pharmacology
  • 1975
    • Corpus ID: 36958671
Ninety-one cats were recorded from the cochlear round window in order to evaluate the degree of N1 depression produced by iv… Expand
1975
1975
A comparison of the diuretic effects of prostaglandin A1, sodium ethacrynate, and placebo.
The comparative diuretic activity of prostaglandin A1 (PGA1), sodium ethacrynate, and placebo was assessed in healthy volunteers… Expand
1975
1975
Effect of diuretics on oxidative phosphorylation of dog kidney mitochondria.
An effect of diuretics on cellular metabolism has been shown. In order to examine further the direct effect of diuretics on renal… Expand
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