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Estramustine Phosphate Sodium
Known as:
Phosphate Sodium, Estramustine
, estra-1,3,5(10)-triene-3,17-diol(17(beta))-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt, monohydrate
, Estramustine Sodium Phosphate
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The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that combines estradiol and nornitrogen mustard…
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National Institutes of Health
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Related topics
Related topics
14 relations
Alkylating Activity [MoA]
Drug Allergy
Estradiol
Estramustine phosphate
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Narrower (2)
Emcyt
Estracyt
Broader (1)
Estramustine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
An active regimen of weekly paclitaxel and estramustine in metastatic androgen-independent prostate cancer.
U. Vaishampayan
,
J. Fontana
,
W. Du
,
M. Hussain
Urology
2002
Corpus ID: 23622253
Review
2001
Review
2001
Necessity of re‐evaluation of estramustine phosphate sodium (EMP) as a treatment option for first‐line monotherapy in advanced prostate cancer
T. Kitamura
International journal of urology
2001
Corpus ID: 43384150
Abstract Estramustine phosphate sodium (EMP) was first introduced in the early 1970s for the treatment of prostate cancer, when…
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Highly Cited
1998
Highly Cited
1998
Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells.
N. Laing
,
M. Belinsky
,
+5 authors
K. Tew
Cancer Research
1998
Corpus ID: 13327202
An estramustine-resistant human ovarian carcinoma cell line, SKEM, was generated to explore resistance mechanisms associated with…
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Review
1998
Review
1998
Pharmacokinetics and Pharmacodynamics of Estramustine Phosphate
A. Bergenheim
,
R. Henriksson
Clinical Pharmacokinetics
1998
Corpus ID: 1943973
Estramustine phosphate (estramustine phosphate sodium), a carbamate ester combining 17β-estradiol and nor-nitrogen mustard, is a…
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Highly Cited
1996
Highly Cited
1996
Treatment of hormone-refractory prostate cancer with 90Y-CYT-356 monoclonal antibody.
N. Deb
,
M. Goris
,
+6 authors
S. Knox
Clinical Cancer Research
1996
Corpus ID: 23105335
A Phase I dose-escalation study using 90Y-CYT-356 monoclonal antibody was performed in 12 patients with hormone-refractory…
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Review
1995
Review
1995
Estramustine Phosphate Sodium
C. Perry
,
D. McTavish
Drugs & Aging
1995
Corpus ID: 36725810
SummarySynopsisEstramustine phosphate sodium (estramustine phosphate), a unique antitumour agent, is selectively taken up by…
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1992
1992
Evidence for a non‐estrogenic cytostatic effect of estramustine on human prostatic carcinoma cells in vivo
S. Eklöv
,
S. Nilsson
,
A. Larson
,
P. Björk
,
B. Hartley‐åsp
The Prostate
1992
Corpus ID: 43212577
Estramustine is one of the main metabolites of estramustine phosphate (EstracytR), a drug used in the treatment of advanced…
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Review
1991
Review
1991
Heterosteroids and drug research.
H. Singh
,
D. P. Jindal
,
M. Yadav
,
M. Kumar
Progress in Medicinal Chemistry
1991
Corpus ID: 12226165
Highly Cited
1988
Highly Cited
1988
Estramustine binds MAP-2 to inhibit microtubule assembly in vitro.
M. Stearns
,
K. Tew
Journal of Cell Science
1988
Corpus ID: 28634323
We have investigated the ability of estramustine to bind to rat brain microtubule-associated proteins (MAPs) and purified MAP-2…
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1985
1985
Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets.
M. Stearns
,
D. P. Jenkins
,
K. Tew
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 31270801
Fluorescence-microscopic studies with dansylated estramustine (DnsEM) has permitted investigation of the mechanism of…
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