FAQ

Estramustine Phosphate Sodium

Known as: Phosphate Sodium, Estramustine, estra-1,3,5(10)-triene-3,17-diol(17(beta))-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt, monohydrate, Estramustine sodium phosphate 
The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that combines estradiol and nornitrogen mustard… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2013
012319792013

Related topics

Related topics

15 relations
Alkylating Activity [MoA]Drug AllergyEstradiolEstramustine phosphate
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Narrower (2)

EmcytEstracyt

Broader (1)

Estramustine

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Estramustine Phosphate Sodium
Drug Allergy
Prostatic Neoplasms
Estradiol
Thromboembolism
Thrombophlebitis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature.
This retrospective chart review study was conducted to evaluate the efficacy of estramustine phosphate sodium hydrate (EMP… (More)
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2010
2010
[Effect of the 5-HT3 receptor antagonist granisetron on estramustine phosphate sodium (Estracyt)-induced emesis in ferrets].
Estracyt(R) is an antimitotic drug used for the treatment of prostate cancer, and its most common adverse effects are nausea and… (More)
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2005
2005
Single-nucleotide polymorphisms in the 17beta-hydroxysteroid dehydrogenase genes might predict the risk of side-effects of estramustine phosphate sodium in prostate cancer patients.
BACKGROUND Estramustine phosphate sodium (EMP) frequently causes side-effects such as gastrointestinal discomfort, nausea, and… (More)
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2004
2004
[A clinical study of estramustine phosphate sodium for the treatment of hot flushes in men with prostate cancer].
PURPOSE To assess the effectiveness and tolerability of estramustine sodium phosphate in men with hot flushes during combined… (More)
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Review
1998
Review
1998
Pharmacokinetics and pharmacodynamics of estramustine phosphate.
Estramustine phosphate (estramustine phosphate sodium), a carbamate ester combining 17 beta-estradiol and nor-nitrogen mustard… (More)
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Review
1995
Review
1995
Estramustine phosphate sodium. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer.
Estramustine phosphate sodium (estramustine phosphate), a unique antitumour agent, is selectively taken up by prostate cells and… (More)
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1991
1991
The effect of estramustine derivatives on microtubule assembly in vitro depends on the charge of the substituent.
Estramustine, and derivatives of estramustine with a charged substituent at position 17 on the estrogen moiety, have been… (More)
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1989
1989
Proteolytic cleavage of high-molecular-weight microtubule-associated proteins by the prostatic estramustine-binding protein.
The rat prostatic estramustine-binding protein was found to inhibit assembly of microtubules in a concentration-dependent manner… (More)
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1985
1985
Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets.
Fluorescence-microscopic studies with dansylated estramustine (DnsEM) has permitted investigation of the mechanism of… (More)
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Review
1984
Review
1984
Estramustine phosphate sodium.
Estramustine phosphate is approved by the Food and Drug Administration for oral use in the palliative treatment of patients with… (More)
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