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Estramustine Phosphate Sodium

Known as: Phosphate Sodium, Estramustine, estra-1,3,5(10)-triene-3,17-diol(17(beta))-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt, monohydrate, Estramustine Sodium Phosphate 
The orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that combines estradiol and nornitrogen mustard… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
OBJECTIVES The efficacy of weekly high-dose paclitaxel in androgen-independent prostate carcinoma and its cytotoxic synergy with… Expand
Review
2001
Review
2001
  • T. Kitamura
  • International journal of urology : official…
  • 2001
  • Corpus ID: 43384150
Abstract Estramustine phosphate sodium (EMP) was first introduced in the early 1970s for the treatment of prostate cancer, when… Expand
Highly Cited
1998
Highly Cited
1998
An estramustine-resistant human ovarian carcinoma cell line, SKEM, was generated to explore resistance mechanisms associated with… Expand
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Highly Cited
1996
Highly Cited
1996
  • N. Deb, M. Goris, +6 authors S. Knox
  • Clinical cancer research : an official journal of…
  • 1996
  • Corpus ID: 23105335
A Phase I dose-escalation study using 90Y-CYT-356 monoclonal antibody was performed in 12 patients with hormone-refractory… Expand
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Review
1995
Review
1995
SummarySynopsisEstramustine phosphate sodium (estramustine phosphate), a unique antitumour agent, is selectively taken up by… Expand
1992
1992
Estramustine is one of the main metabolites of estramustine phosphate (EstracytR), a drug used in the treatment of advanced… Expand
1991
1991
Estramustine, and derivatives of estramustine with a charged substituent at position 17 on the estrogen moiety, have been… Expand
Highly Cited
1988
Highly Cited
1988
We have investigated the ability of estramustine to bind to rat brain microtubule-associated proteins (MAPs) and purified MAP-2… Expand
1985
1985
Fluorescence-microscopic studies with dansylated estramustine (DnsEM) has permitted investigation of the mechanism of… Expand
Review
1984
Review
1984
Estramustine phosphate is approved by the Food and Drug Administration for oral use in the palliative treatment of patients with… Expand
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