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Epirizole

Known as: Mepirizole, Methopyrimazole, Polihexanid 
4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine. A pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

Anti-Inflammatory Agents, Non-Steroidal
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

Mebron

Papers overview

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2011
2011
Schmerzreduktion bei Patienten mit chronischem Ulcus cruris durch ein neu entwickeltes Morphingel
ZusammenfassungHintergrundNeben der essenziell wichtigen Diagnostik und Behandlung der zugrunde liegenden Erkrankungen ist es ein… 
Highly Cited
1999
Highly Cited
1999
Structural and cytotoxic study of new Pt(II) and Pd(II) complexes with the bi-heterocyclic ligand mepirizole.
1999
1999
Effects of S‐0509, a novel CCKB/gastrin receptor antagonist, on acid secretion and experimental duodenal ulcers in rats
S‐0509, 2‐[(tert‐butoxycarbonylmethyl) [(m‐(carboxy‐phenyl)‐ureidomethyl‐carbonyl]] aminobenzo phenone, was developed as a potent… 
1996
1996
Synthesis and cytoprotective antiulcer activity of 2- or 4-(1H-pyrazol-1-yl)pyrimidine derivatives related to mepirizole and dulcerozine.
(1H-Pyrazol-1-yl)-, (1H-imidazol-1-yl)-, and (1H-1,2,4-triazol-1-yl)pyrimidines were prepared and evaluated for cytoprotective… 
Highly Cited
1994
Highly Cited
1994
On the absorption of alendronate in rats.
Alendronate is an antiosteolytic agent under investigation for the treatment of a number of bone disorders. Since the compound is… 
1989
1989
Pathogenesis of the earliest epithelial cell damage induced by mepirizole and cysteamine in the rat duodenum.
Mepirizole (200 mg/kg) and cysteamine (100 mg/kg) induced epithelial cell damage in the proximal duodenum of rats within 30 min… 
Highly Cited
1986
Highly Cited
1986
Central and peripheral analgesic action of non-acidic non-steroidal anti-inflammatory drugs in mice and rats.
The site of the analgesic action of non-acidic (basic), non-steroidal anti-inflammatory drugs (NSAIDs) was investigated in the… 
1986
1986
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
Biochemical and pharmacological properties of a newly synthesized compound, 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC… 
1984
1984
Decrease in alkaline secretion during duodenal ulceration induced by mepirizole in rats
1981
1981
Rectal delivery of antiinflammatory drugs. I. The influence of antiinflammatory drugs on rectal absorption of beta-lactam antibiotics.
The effects of non-steroid antiinflammatory (NSAI) drugs on the rectal membrane were studied by measuring the change in the… 
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