Eosinophil cationic protein

Known as: Ribonuclease, Eosinophil-Associated, RNase 3, Eosinophil-Associated Ribonuclease 
One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil cationic protein is a 21-kDa cytotoxic peptide with a pI of… (More)
National Institutes of Health

Papers overview

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Review
2001
Review
2001
Eosinophils remain among the most enigmatic of cells, as our appreciation of their detrimental activities--e.g., asthma and… (More)
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Highly Cited
2000
Highly Cited
2000
Eotaxin and other CC chemokines acting via CC chemokine receptor-3 (CCR3) are believed to play an integral role in the… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Airway eosinophilic inflammation is a characteristic feature of asthma. This can be assessed directly by measurement… (More)
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Highly Cited
1996
Highly Cited
1996
Methods to examine sputum for indices of airway inflammation are evolving. We have examined the repeatability and the validity of… (More)
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Highly Cited
1995
Highly Cited
1995
Eosinophil cationic protein (ECP) is a toxin secreted by activated human eosinophils that has anti-parasitic, antibacterial, and… (More)
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Highly Cited
1989
Highly Cited
1989
We examined the bactericidal activity of two proteins that are abundant in the cytoplasmic granules of human eosinophils, major… (More)
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Highly Cited
1989
Highly Cited
1989
We tested the effects of four eosinophil granule cationic proteins: major basic protein (MBP), eosinophil cationic protein (ECP… (More)
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Highly Cited
1989
Highly Cited
1989
Eosinophils play an important role as effector cells in allergic, parasitic, and other conditions. The mechanism(s) by which… (More)
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Highly Cited
1987
Highly Cited
1987
Eosinophilic endomyocardial disease is a complication of the hypereosinophilic syndrome and of several other disorders associated… (More)
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Highly Cited
1986
Highly Cited
1986
Recent evidence suggests a role for eosinophil granule proteins in contact-dependent antibody-mediated cytotoxicity1–3. Cytolysis… (More)
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