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Effector T-Lymphocyte

Known as: Effector T Lymphocyte, Effector T Cells, Effector T Cell 
A mature T-lymphocyte that has differentiated into a form that can mount an antigen-specific immune response.
National Institutes of Health

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Related topics

2 relations
Hematopoietic and Lymphoid TissueLymphoid Tissue

Papers overview

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2018
2018
Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer
Agents targeting the PD1-PDL1 axis have transformed cancer therapy. Factors that influence clinical response to PD1-PDL1… Expand
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2017
2017
Curtailed T‐cell activation curbs effector differentiation and generates CD8+ T cells with a naturally‐occurring memory stem cell phenotype
Human T memory stem (TSCM ) cells with superior persistence capacity and effector functions are emerging as important players in… Expand
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2017
2017
High‐dose wogonin exacerbates DSS‐induced colitis by up‐regulating effector T cell function and inhibiting Treg cell
Wogonin exerts anti-tumour activities via multiple mechanisms. We have identified that high-dose wogonin (50 or 100 mg/kg) could… Expand
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2016
2016
Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.
Constitutive proteasomes (c-20S) are ubiquitously expressed cellular proteases that degrade polyubiquitinated proteins and… Expand
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2015
2015
Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.
OBJECTIVE The balance between Treg and effector T cells (Teff) is crucial for immune regulation in JIA. How MTX, the cornerstone… Expand
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2015
2015
Free Extracellular miRNA Functionally Targets Cells by Transfecting Exosomes from Their Companion Cells
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten application produce a suppressive… Expand
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Review
2015
Review
2015
A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders
Aberrant innate and adaptive immune responses are neurodegenerative disease effectors. Disease is heralded by a generalized, but… Expand
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2012
2012
Activated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanoma.
Immunotherapy based on adoptive transfer of tumor antigen-specific CD8(+) T cell (TC) is generally limited by poor in vivo… Expand
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Highly Cited
1998
Highly Cited
1998
Virus-specific CD8+ T cells in primary and secondary influenza pneumonia.
Virus-specific CD8+ effector T cells (eCTL) are enriched in the lungs of mice with primary influenza pneumonia, though later… Expand
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1977
1977
Different h-2 requirements for triggering precursor t-cell induction or lysis by effector t cells defined by the balb/c-h- -2db mutation.
 
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