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EZN 2968
Known as:
EZN-2968
, EZN2968
National Institutes of Health
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Related topics
Related topics
2 relations
Anti-HIF-1alpha LNA Antisense Oligonucleotide EZN-2968
Broader (1)
Oligonucleotides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Stage-Specific Effects of Hypoxia on Interstitial Lung Disease
S. Artham
,
P. R. Somanath
2017
Corpus ID: 55849908
Interstitial lung disease (ILD) comprises a group of lung diseases principally affecting the pulmonary interstitium, for example…
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2016
2016
EZN-2968, a novel hypoxia-inducible factor-1α (HIF-1α) messenger ribonucleic acid (mRNA) antagonist: Results of a phase I, pharmacokinetic (PK), dose-escalation study of daily administration in…
A. Patnaik
,
E. Chiorean
,
+6 authors
A. Buchbinder
Journal of Clinical Oncology
2016
Corpus ID: 40356714
2564 Background: HIF-1 is a transcription factor that regulates expression of many key genes, notably those switching cell…
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Highly Cited
2014
Highly Cited
2014
Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
W. Jeong
,
A. Rapisarda
,
+8 authors
S. Kummar
Cancer Chemotherapy and Pharmacology
2014
Corpus ID: 30107141
AbstractPurpose Hypoxia-inducible factor-1 (HIF-1) facilitates the adaptation of normal and tumor tissues to oxygen deprivation…
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2014
2014
HIF-1α inhibition blocks the cross talk between multiple myeloma plasma cells and tumor microenvironment.
E. Borsi
,
G. Perrone
,
+9 authors
M. Cavo
Experimental Cell Research
2014
Corpus ID: 19923805
Highly Cited
2014
Highly Cited
2014
Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma
E. Borsi
,
G. Perrone
,
+11 authors
M. Cavo
OncoTarget
2014
Corpus ID: 3924676
The increasing importance of hypoxia-inducible factor-1α (HIF-1α) in tumorigenesis raises the possibility that agents which…
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2013
2013
Abstract 95: Inhibiiton of non-hypoxic HIF-1 expression in letrozole-resistant breast cancer cells reduces their cancer stem cell characteristics.
A. Kazi
,
P. Shah
,
A. Schech
,
G. Sabnis
,
S. Chumsri
,
A. Brodie
2013
Corpus ID: 76083985
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Although aromatase inhibitors (AIs) have been shown…
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2011
2011
Abstract LB-407: Down-modulation of mRNA by EZN-2968, an hypoxia-inducible factor-1α (HIF-1α) mRNA antagonist, administered in adult patients with advanced solid tumors
R. Cohen
,
A. Olszanski
,
+5 authors
A. Buchbinder
2011
Corpus ID: 57662959
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Background : HIF-1 is a transcription factor that is a…
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Highly Cited
2008
Highly Cited
2008
A RNA antagonist of hypoxia-inducible factor-1α, EZN-2968, inhibits tumor cell growth
L. Greenberger
,
I. Horak
,
+6 authors
H. Ørum
Molecular Cancer Therapeutics
2008
Corpus ID: 30759409
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays a critical role in angiogenesis, survival, metastasis…
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2008
2008
Inhibition of hypoxia inducible factor-1 α (HIF-1α) by an RNA antagonist, EZN-2968, in vitro and in vivo.
L. Greenberger
,
D. Filpula
,
+5 authors
I. Horak
2008
Corpus ID: 81675449
1570 Inhibition of hypoxia inducible factor-1 α (HIF-1α) by an RNA antagonist, EZN-2968, in vitro and in vivo. 1Enzon…
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Review
1972
Review
1972
The zeta function of toral endomorphisms
J. England
1972
Corpus ID: 121675768
In this note we give a completely elementary way to compute the number of fixed points of a certain class of toral endomorphisms…
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