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EZN 2968

Known as: EZN-2968, EZN2968 
 

Topic mentions per year

Topic mentions per year

2008-2013
0120082013

Related topics

Related topics

1 relation

Broader (1)

Oligonucleotides

Related mentions per year

Related mentions per year

1950-2018
1960198020002020
EZN 2968
Oligonucleotides

Papers overview

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2014
2014
Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma
The increasing importance of hypoxia-inducible factor-1α (HIF-1α) in tumorigenesis raises the possibility that agents which… (More)
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2014
2014
HIF-1α inhibition blocks the cross talk between multiple myeloma plasma cells and tumor microenvironment.
Multiple myeloma (MM) is a malignant disorder of post-germinal center B cells, characterized by the clonal proliferation of… (More)
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2013
2013
Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
Hypoxia-inducible factor-1 (HIF-1) facilitates the adaptation of normal and tumor tissues to oxygen deprivation. HIF-1 is… (More)
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2010
2010
[HIV-1 eradication with the "shock and kill" strategy].
© 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.pharmuz.de 3/2010 (39) | Pharm. Unserer Zeit | 171 Moleküls bilden… (More)
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2009
2009
EZN-2968, a novel hypoxia-inducible factor-1α (HIF-1α) messenger ribonucleic acid (mRNA) antagonist: Results of a phase I, pharmacokinetic (PK), dose-escalation study of daily administration in…
2564 Background: HIF-1 is a transcription factor that regulates expression of many key genes, notably those switching cell… (More)
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Highly Cited
2008
Highly Cited
2008
A RNA antagonist of hypoxia-inducible factor-1alpha, EZN-2968, inhibits tumor cell growth.
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays a critical role in angiogenesis, survival, metastasis… (More)
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