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EWSR1 wt Allele

Known as: EWS RNA-Binding Protein 1 wt Allele, EWS, AC002059.7 
Human EWSR1 wild-type allele is located in the vicinity of 22q12.2 and is approximately 32 kb in length. This allele, which encodes RNA-binding… 
National Institutes of Health

Related topics

Related topics

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22q12.2Desmoplastic Small Round Cell TumorEWSR1 geneEwing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pre‐B‐cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma
We report a 2‐year‐old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a… 
2010
2010
Detection of SYT and EWS gene rearrangements by dual-color break-apart CISH in liquid-based cytology samples of synovial sarcoma and Ewing sarcoma/primitive neuroectodermal tumor.
To improve cytologic diagnostic accuracy for translocation-associated sarcomas, we explored dual-color break-apart (dc… 
2010
2010
Feasibility of bevacizumab (NSC 704865, BB-IND# 7921) combined with vincristine, topotecan, and cyclophosphamide in patients with first recurrent Ewing sarcoma (EWS): A Children's Oncology Group (COG…
9552 Background: The importance of angiogenesis in EWS has been well explored and activity of angiogenesis inhibitors observed in… 
2010
2010
EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells.
2009
2009
High-dose chemotherapy with autologous stem cell transplantation for relapsed Ewing's sarcoma.
10545 Background: Nearly 30-40% of patients with newly diagnosed, non-metastatic Ewing's Sarcoma (EWS) relapse. Post-relapse… 
2005
2005
Molecular detection of EWS-Ets fusion transcripts and their clinicopathologic significance in Ewing's sarcoma/peripheral primitive neuroectodermal tumor.
BACKGROUND Ewing's sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) is often difficult to distinguish from other… 
2003
2003
COL11A2 Collagen Gene Transcription Is Differentially Regulated by EWS/ERG Sarcoma Fusion Protein and Wild-type ERG*
A specific t(21;22) chromosomal translocation creates the chimeric EWS/ERG gene in some cases of Ewing's sarcoma. In the… 
Review
1997
Review
1997
Chromosome translocation-mediated conversion of a tumor suppressor gene into a dominant oncogene: fusion of EWS1 to WT1 in desmoplastic small round cell tumors.
The preceding articles in this volume have provided a unique overview of genetic and biochemical mechanisms which underlie… 
1996
1996
EWS/FLI-1 fusion transcript detection and MIC2 immunohistochemical staining in the diagnosis of Ewing's sarcoma.
Ewing's sarcoma (ES) and other primitive peripheral neuroectodermal tumors (pPNETs) can present a significant diagnostic problem… 
1996
1996
Metastatic extraosseous Ewing tumor. Association of the additional translocation der(16)t(1;16) with the variant EWS/ERG rearrangement in a case of cytogenetically inconspicuous chromosome 22.
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