EWSR1 wt Allele

Known as: EWS RNA-Binding Protein 1 wt Allele, EWS, AC002059.7 
Human EWSR1 wild-type allele is located in the vicinity of 22q12.2 and is approximately 32 kb in length. This allele, which encodes RNA-binding… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The fusion between EWS and ETS family members is a key oncogenic event in Ewing tumors and important EWS-FLI1 target genes have… (More)
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Review
2009
Review
2009
The Ewing sarcoma breakpoint region 1 (EWSR1; also known as EWS) represents one of the most commonly involved genes in sarcoma… (More)
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2009
2009
Ewing's sarcoma is a malignant bone-associated tumor of children and young adults. Most cases of Ewing's sarcoma express the EWS… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The presence of tumor-specific mutations in the cancer genome represents a potential opportunity for pharmacologic… (More)
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Highly Cited
2006
Highly Cited
2006
Tumors of the Ewing's sarcoma family (ESFT), such as Ewing's sarcoma (EWS) and primitive neuroectodermal tumors (PNET), are… (More)
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2004
2004
The defining cytogenetic abnormality of Ewing's sarcoma is the presence of a balanced t(11;22) translocation expressing the EWS… (More)
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Highly Cited
2002
Highly Cited
2002
Ewing's sarcoma is associated with a fusion between the EWS and FLI1 genes, forming an EWS/FLI fusion protein. We developed a… (More)
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2002
2002
We report here that the Id2 (inhibitor of DNA binding 2) gene is a novel target of transcriptional activation by EWS–FLI1 and EWS… (More)
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Highly Cited
1997
Highly Cited
1997
As a result of chromosome translocations, the EWS gene is fused to a variety of transcription factors in human solid neoplasia… (More)
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Highly Cited
1993
Highly Cited
1993
EWS/FLI-1 is a chimeric protein formed by a tumor-specific 11;22 translocation found in both Ewing's sarcoma and primitive… (More)
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