ETV7 gene

Known as: ETS variant 7, TEL-2, TEL2 oncogene 
 
National Institutes of Health

Papers overview

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2014
2014
Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1
Client protein recruitment to the Hsp90 system depends on cochaperones that bind the client and Hsp90 simultaneously and… (More)
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2014
2014
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
The apoptotic actions of p53 require its phosphorylation by a family of phosphoinositide-3-kinase-related-kinases (PIKKs), which… (More)
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2013
2013
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma
The Tel2 (also known as Telo2) and Tti1 proteins control the cellular abundance of mammalian PIKKs and are integral components of… (More)
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Highly Cited
2010
Highly Cited
2010
Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
Mammalian target of rapamycin (mTOR) is a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is a major… (More)
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Highly Cited
2010
Highly Cited
2010
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
We reported previously that the stability of all mammalian phosphatidylinositol 3-kinase-related protein kinases (PIKKs) depends… (More)
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2008
2008
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.
The kinases ATM and ATR (Tel1 and Mec1 in the yeast Saccharomyces cerevisiae) control the response to DNA damage. We report that… (More)
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Highly Cited
2007
Highly Cited
2007
Tel2 Regulates the Stability of PI3K-Related Protein Kinases
We report an unexpected role for Tel2 in the expression of all mammalian phosphatidylinositol 3-kinase-related protein kinases… (More)
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2007
2007
Tel2 is required for activation of the Mrc1-mediated replication checkpoint.
Proteins belonging to the Tel2/Rad-5/Clk-2 family are conserved among eukaryotes and are involved in various cellular processes… (More)
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2007
2007
Profile of Ets gene expression in human breast carcinoma.
BACKGROUND Ets genes encode a family of transcription factors that play key roles in cell proliferation, differentiation and… (More)
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1996
1996
TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae.
The DNA-protein complexes at the ends of linear eukaryotic chromosomes are called the telomeres. In Saccharomyces cerevisiae… (More)
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