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ETV7 gene

Known as: ETS variant 7, TEL-2, TEL2 oncogene 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1
Summary Client protein recruitment to the Hsp90 system depends on cochaperones that bind the client and Hsp90 simultaneously and… Expand
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Highly Cited
2014
Highly Cited
2014
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
The apoptotic actions of p53 require its phosphorylation by a family of phosphoinositide-3-kinase-related-kinases (PIKKs), which… Expand
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Highly Cited
2010
Highly Cited
2010
Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly*
Mammalian target of rapamycin (mTOR) is a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is a major… Expand
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Highly Cited
2010
Highly Cited
2010
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
We reported previously that the stability of all mammalian phosphatidylinositol 3-kinase-related protein kinases (PIKKs) depends… Expand
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Highly Cited
2010
Highly Cited
2010
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.
TEL2 interacts with and is essential for the stability of all phosphatidylinositol 3-kinase-related kinases (PIKKs), but its… Expand
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Highly Cited
2007
Highly Cited
2007
Tel2 Regulates the Stability of PI3K-Related Protein Kinases
We report an unexpected role for Tel2 in the expression of all mammalian phosphatidylinositol 3-kinase-related protein kinases… Expand
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Highly Cited
2007
Highly Cited
2007
Tel2 Is Required for Activation of the Mrc1-mediated Replication Checkpoint*
Proteins belonging to the Tel2/Rad-5/Clk-2 family are conserved among eukaryotes and are involved in various cellular processes… Expand
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Highly Cited
2001
Highly Cited
2001
Tel-2 Is a Novel Transcriptional Repressor Related to the Ets Factor Tel/ETV-6*
We report here the isolation ofTel-2, a novel member of the Ets transcription factor family, with high homology to Tel/ETV-6. Tel… Expand
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2000
2000
Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6.
The ETS family of proteins is a large group of transcription factors implicated in many aspects of normal hematopoietic… Expand
Highly Cited
1996
Highly Cited
1996
TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae.
The DNA-protein complexes at the ends of linear eukaryotic chromosomes are called the telomeres. In Saccharomyces cerevisiae… Expand
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