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ES-285

National Institutes of Health

Papers overview

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2011
2011
SummaryBackground ES-285 (spisulosine) is a novel compound derived from the marine mollusk Spisula polynoma with evidence of… Expand
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2011
2011
An improved four-step approach for the stereoselective synthesis of long-chain anti-2-amino-3-alkanols is described. Using this… Expand
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2010
2010
SummaryBackground ES-285 (Spisulosine) is a novel marine compound with antitumor activity in preclinical studies. A phase I study… Expand
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2009
2009
A dose-escalation, phase I study evaluated the safety, pharmacokinetics, pharmacogenomics, and efficacy of ES-285, a novel agent… Expand
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Highly Cited
2008
Highly Cited
2008
During the past decades, intense attention has been focused on the anti-tumor properties of marine compounds which some of them… Expand
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Review
2008
Review
2008
The chemical, biological and ecological diversity of the marine ecosystem has contributed immensely in the discovery of extremely… Expand
2005
2005
4111 Introduction: ES-285 is a novel anti-cancer agent originally isolated from the North Atlantic Clam, Spisula polynyma… Expand
Highly Cited
2004
Highly Cited
2004
Nature has been instrumental as a source for therapeutics. Despite the fact that we live in an oceanic planet, a number of… Expand
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2003
2003
Chromophor and fluorophor addition reactions involving phenylisothiocyanate (PITC) and dansyl chloride (DC) were optimized to… Expand
2003
2003
A method was developed for the quantitative analysis of the novel anticancer agent ES-285 (spisulosine; free base) in human… Expand