ERN1 protein, human

Known as: IRE1 protein, human, Ire1-alpha, Endoplasmic Reticulum-To-Nucleus Signaling 1 
Serine/threonine-protein kinase/endoribonuclease IRE1 (977 aa, ~110 kDa) is encoded by the human ERN1 gene. This protein is involved in both protein… (More)

Topic mentions per year

Topic mentions per year

2005-2018
051020052018

Papers overview

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2013
2013
Diego A Rodriguez, Sebastian Zamorano, Fernanda Lisbona, Diego Rojas-Rivera, Hery Urra, Juan R Cubillos-Ruiz, Ricardo Armisen… (More)
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2013
2013
Quan Qiu, Ze Zheng, Lin Chang, Yuan-Si Zhao, Can Tan, Aditya Dandekar, Zheng Zhang, Zhenghong Lin, Ming Gui, Xiu Li, Tongshuai… (More)
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Highly Cited
2012
Highly Cited
2012
yeasts have rewired many regulatory networks, such that processes as diverse as ribosomal protein gene regulation, galactose… (More)
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2012
2012
Endoplasmic reticulum (ER)-mediated protein secretion and quality control have been shown to play an important role in immune… (More)
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2012
2012
IRE1, an ER-localized transmembrane protein, plays a central role in the unfolded protein response (UPR). IRE1 senses the… (More)
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2012
2012
BMP2 (bone morphogenetic protein 2) is known to activate unfolded protein response signaling molecules, including XBP1S and ATF6… (More)
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2012
2012
PS-341 (bortezomib), a proteasome inhibitor, has been approved for the treatment ofmultiplemyeloma.Our previous work has shown… (More)
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2010
2010
IRE1a is an endoplasmic reticulum (ER)-located transmembrane RNase that plays a central role in the ER stress response. Upon ER… (More)
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2008
2008
Background: The endoplasmic reticulum (ER) is a cellular compartment for the biosynthesis and folding of newly synthesized… (More)
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2005
2005
Endoplasmic reticulum (ER) stress leads to activation of caspase-12, which in turn can lead to activation of caspase-3 and cell… (More)
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