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ERN1 protein, human
Known as:
IRE1 protein, human
, Ire1-alpha
, Endoplasmic Reticulum-To-Nucleus Signaling 1
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Serine/threonine-protein kinase/endoribonuclease IRE1 (977 aa, ~110 kDa) is encoded by the human ERN1 gene. This protein is involved in both protein…
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National Institutes of Health
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Related topics
Related topics
21 relations
Alzheimer's Disease Pathway KEGG
ERN1 gene
Enzyme Gene
Esterase Gene
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Broader (2)
Endoribonucleases
Protein-Serine-Threonine Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nicardipine induces apoptosis via IRE1 activation in the PC12 cells
Ji-Hye Song
,
O. Kwon
,
Kisang Kwon
,
Ji-Young Choi
,
Seung-Whan Kim
2018
Corpus ID: 55962966
Although an endoplasmic reticulum (ER) induction by calcium-channel blocker has been reported, the mechanism of ER stress…
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2017
2017
Unfolded Protein Response Signaling Pathway Regulates Cardiac Function in Heart Failure with Preserved Ejection Fraction
G. Schiattarella
2017
Corpus ID: 181570488
Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome effecting more than 3 million people in the United…
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2016
2016
IRE 1 a mediates PKR activation in response to Chlamydia trachomatis infection
S. Webster
,
L. Ellis
,
+8 authors
J. Goodall
2016
Corpus ID: 55552785
Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non…
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2015
2015
Effect ofmodulation of unfolded protein response pathway on dengue virus infection
D. Diwaker
,
K. Mishra
,
L. Ganju
2015
Corpus ID: 5872687
The unfolded protein response (UPR) is a cascade of events that helps restoring cellular homeostasis under stressful conditions…
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Review
2015
Review
2015
Endoplazmik Retikulum Stresi ve Pankreas Kanseri
Kemal Ergin
,
Esra Gokmen
2015
Corpus ID: 75446927
Endoplasmic reticulum (ER) stress, which results from different stimuli, is an important cellular event. There are different…
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2014
2014
Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration : involvement of the proteasome and ER stress-activated kinase IRE 1 a
A. Hyrskyluoto
,
C. Bruelle
,
+8 authors
L. Korhonen
2014
Corpus ID: 53381556
Huntington’s disease (HD) is an autosomal inherited neurological disease caused by a CAG-repeat expansion in the first exon of…
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2014
2014
First aid for a damaged proteome.
Nature Chemical Biology
2014
Corpus ID: 20822487
2012
2012
Human Cancer Biology Protein KinaseCK 2 ProtectsMultipleMyelomaCells fromER Stress – Induced Apoptosis and from the Cytotoxic Effect of HSP 90 Inhibition through Regulation of the Unfolded Protein…
S. Manni
,
Alessandra Brancalion
,
+16 authors
F. Piazza
2012
Corpus ID: 38648742
Purpose: Protein kinase CK2 promotes multiple myeloma cell growth by regulating critical signaling pathways. CK2 also modulates…
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2012
2012
The role of IRE1a in lipid homeostasis
S. Wang
,
R. Kaufman
2012
Corpus ID: 76135593