ERN1 gene

Known as: IRE1-ALPHA, ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1, endoplasmic reticulum to nucleus signaling 1 
This gene is involved in both protein phosphorylation and mRNA splicing.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
05010019912017

Papers overview

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Highly Cited
2007
Highly Cited
2007
Endoplasmic reticulum (ER) stress activates a set of signaling pathways, collectively termed the unfolded protein response (UPR… (More)
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Highly Cited
2006
Highly Cited
2006
Bernd Bukau,1 Jonathan Weissman,2 and Arthur Horwich3,4,* 1Zentrum fur Molekulare Biologie, Universität Heidelberg, 69120… (More)
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Highly Cited
2006
Highly Cited
2006
The unfolded protein response (UPR) allows the endoplasmic reticulum (ER) to recover from the accumulation of misfolded proteins… (More)
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Highly Cited
2006
Highly Cited
2006
Accumulation of misfolded protein in the endoplasmic reticulum (ER) triggers an adaptive stress response-termed the unfolded… (More)
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Highly Cited
2006
Highly Cited
2006
In pancreatic beta cells, the endoplasmic reticulum (ER) is an important site for insulin biosynthesis and the folding of newly… (More)
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Highly Cited
2002
Highly Cited
2002
The unfolded protein response (UPR), caused by stress, matches the folding capacity of endoplasmic reticulum (ER) to the load of… (More)
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Highly Cited
2001
Highly Cited
2001
In yeast, the transmembrane protein kinase/endoribonuclease Ire1p activated by endoplasmic reticulum stress cleaves HAC1 mRNA… (More)
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Highly Cited
2000
Highly Cited
2000
Malfolded proteins in the endoplasmic reticulum (ER) induce cellular stress and activate c-Jun amino-terminal kinases (JNKs or… (More)
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Highly Cited
2000
Highly Cited
2000
PERK and IRE1 are type-I transmembrane protein kinases that reside in the endoplasmic reticulum (ER) and transmit stress signals… (More)
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Highly Cited
1993
Highly Cited
1993
The transcription of genes encoding soluble proteins that reside in the endoplasmic reticulum (ER) is induced when unfolded… (More)
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