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ERCC6 protein, human

Known as: Cockayne Syndrome B Repair Protein, Cockayne Syndrome Protein CSB, ATP-Dependent Helicase ERCC6 
DNA excision repair protein ERCC-6 (1493 aa, ~168 kDa) is encoded by the human ERCC6 gene. This protein plays a role in transcription-coupled DNA… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
UV-sensitive syndrome (UVSS) is an autosomal recessive disorder characterized by photosensitivity and deficiency in transcription… Expand
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Highly Cited
2009
Highly Cited
2009
Laryngeal cancer is known to be associated with smoking and high alcohol consumption. Nucleotide excision repair (NER) plays a… Expand
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Highly Cited
2008
Highly Cited
2008
The DNA repair gene ERCC6, an important caretaker of the overall genome stability, is thought to play a role in the development… Expand
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Highly Cited
2006
Highly Cited
2006
This study investigates age-related macular degeneration (AMD) genetic risk factors through identification of a functional single… Expand
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Highly Cited
2006
Highly Cited
2006
Cockayne syndrome (CS) is an inherited neurodevelopmental disorder with progeroid features. Although the genes responsible for CS… Expand
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Highly Cited
1997
Highly Cited
1997
Cockayne's syndrome (CS) is a disease characterized by developmental and growth defects, sunlight sensitivity, and a defect in… Expand
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Highly Cited
1997
Highly Cited
1997
Transcription is coupled to repair in Escherichia coli and in humans. Proteins encoded by the mfd gene in E. coli and by the… Expand
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Highly Cited
1994
Highly Cited
1994
Transcription-coupled repair (TCR) is a universal sub-pathway of the nucleotide excision repair (NER) system that is limited to… Expand
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1993
1993
The human repair gene ERCC6--a presumed DNA (or RNA) helicase--has recently been found to function specifically in preferential… Expand
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Highly Cited
1992
Highly Cited
1992
Cells from patients with the UV-sensitive nucleotide excision repair disorder Cockayne's syndrome (CS) have a specific defect in… Expand
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