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ERBIN gene

Known as: ERBIN, ERBB2 INTERACTING PROTEIN, LAP2 
This gene is involved in signal transduction and protein localization and function.
National Institutes of Health

Related topics

Related topics

7 relations
ERBB2 Interacting Protein, HumanHomo sapiensIntracellular TransportLigand Binding

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ERBB2IP wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.
Genetic disorders of the Ras/MAPK pathway, termed RASopathies, produce numerous abnormalities, including cutaneous keratodermas… 
Highly Cited
2006
Highly Cited
2006
Role for Erbin in Bacterial Activation of Nod2
ABSTRACT Intracellular peptidoglycan (PG) recognition in human cells is mediated by the NACHT-LRR proteins Nod1 and Nod2… 
Highly Cited
2006
Highly Cited
2006
Erbin Inhibits RAF Activation by Disrupting the Sur-8-Ras-Raf Complex*
Erbin is a member of the LAP (leucine-rich repeat (LRR) and PDZ domain) family. It inhibits Ras-mediated activation of ERK in… 
Highly Cited
2003
Highly Cited
2003
Origins of PDZ Domain Ligand Specificity
The LAP (leucine-rich repeatand PDZ-containing) family of proteins play a role in maintaining epithelial and neuronal cell size… 
Highly Cited
2003
Highly Cited
2003
Novel Mode of Ligand Recognition by the Erbin PDZ Domain*
Erbin contains a class I PDZ domain that binds to the C-terminal region of the receptor tyrosine kinase ErbB2, a class II ligand… 
Highly Cited
2003
Highly Cited
2003
Identification of three novel Smad binding proteins involved in cell polarity
Highly Cited
2002
Highly Cited
2002
The Erbin PDZ Domain Binds with High Affinity and Specificity to the Carboxyl Termini of δ-Catenin and ARVCF*
Erbin is a recently described member of the LAP (leucine-rich repeat and PDZ domain) protein family. We used a C-terminally… 
Highly Cited
2001
Highly Cited
2001
The ERBB2/HER2 Receptor Differentially Interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 Domain Proteins*
Identification of protein complexes associated with the ERBB2/HER2 receptor may help unravel the mechanisms of its activation and… 
Highly Cited
2000
Highly Cited
2000
ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor
The ERBB receptors have a crucial role in morphogenesis and oncogenesis. We have identified a new PDZ protein we named ERBIN… 
Highly Cited
2000
Highly Cited
2000
Collective nomenclature for LAP proteins
In 1996 Mary Kennedy and colleagues isolated the protein Densin-180 from the rbat postsynaptic density. This protein had a unique… 
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