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ERBB3 wt Allele

Known as: EGF Receptor 3 Gene, HER3, V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) wt Allele 
Human ERBB3 wild-type allele is located within 12q13 and is approximately 23 kb in length. This allele, which encodes receptor tyrosine-protein… 
National Institutes of Health

Related topics

Related topics

13 relations
12q13Cell ProliferationERBB2 Signaling PathwayERBB3 Receptor Protein-Tyrosine Kinase

Broader (1)

ERBB3 gene

Papers overview

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2014
2014
Combination of her3 / egfr inhibitor compound Mek inhibitor compounds and methods of use
The present invention provides a combination comprising MEK inhibitors (such as GDC-0973 or GDC-0623) or a pharmaceutically… 
2014
2014
Investigating a role of HER3 in anti-HER2 target therapy in breast cancer
2014
2014
Investigating a role of HER3 in anti-HER2 target therapy in breast cancer
Background HER2-positive breast cancer is a poor prognostic subgroup, even if treated with anti-HER2 directed therapy… 
2014
2014
Combination mEq inhibitor compound with a compound inhibitor her3 / egfr and methods of use
2013
2013
Abstract P4-16-09: Phase 1b/2 trial of the HER3 inhibitor patritumab (U3-1287) in combination with trastuzumab plus paclitaxel in newly-diagnosed patients with HER2+ metastatic breast cancer (MBC)
Background: Patritumab is a fully human anti-HER3 monoclonal antibody that has shown potent antitumor activity in vivo . HER3 is… 
2013
2013
Diagnosis and treatments associated with her3 inhibitors
1. A method for treating type of cancer in a patient comprising administering a therapeutically effective amount of an inhibitor… 
2012
2012
Abstract P5-19-01: Targeting the HER3-phosphatidyl inositol-3 kinase pathway in breast cancers
Background: Using a mouse model of HER3 ablation in the mammary epithelium, we previously showed that HER3 is required for the… 
2012
2012
Antibody 3 (her3) epidermal growth factor receptor
The present invention is directed to the HER family receptors, HER3 receptor interactions e.g. antibody or fragment thereof. In… 
2010
2010
Cell line and drug-dependent effect of ERBB3 on cancer cell proliferation, chemosensitivity, and multidrug actions
Correspondence: Jin-Xiong She Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street… 
2010
2010
Genetics: HER3 overexpression in breast cancer conveys a poor prognosis
a highly promising and clinically applicable candidate.” tumor samples from 4,046 patients with invasive breast carcinoma were…