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ERBB3 gene
Known as:
HER3
, TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER3
, V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Gene
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This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated…
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National Institutes of Health
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Related topics
Related topics
10 relations
Cell Proliferation
ERBB3 Receptor Protein-Tyrosine Kinase
ERBB3 protein, human
Ligand Binding
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Narrower (1)
ERBB3 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract 3989: Dual targeting of ErbB2/ErbB3 for treatment of SCL3A2-NRG1-mediated lung cancer
Jeong Yeon Jo
,
Dong-Hoon Shin
,
Ji-Youn Han
Experimental and Molecular Therapeutics
2018
Corpus ID: 81287755
We previously identified an oncogenic fusion gene involving the 5′ region of SLC3A2 and the 3′ region of NRG1 in a patient with…
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2016
2016
GENT-35. MicroRNA miR100 INHIBITS GLIOBLASTOMA GROWTH BY TARGETING SMARCA5 AND ERBB3 IN GBM STEM-LIKE CELLS VIA TWO DISTINCT TRANSCRIPTS
Bahauddeen M. Alrfaei
,
R. Vemuganti
,
J. Kuo
2016
Corpus ID: 78703684
2016
2016
Engineering strategies for ABD-derived affinity proteins for therapeutic and diagnostic applications
Mikael Åstrand
2016
Corpus ID: 78087225
Small stable protein domains are attractive scaffolds for engineering affinity proteins due to their high tolerance to…
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2014
2014
Phase 3 study of patritumab plus erlotinib in EGFR wild-type subjects with advanced non-small cell lung cancer
L. Paz-Ares
,
J. Pawel
,
+4 authors
R. Beckman
2014
Corpus ID: 97005724
• Many patients with advanced non–small cell lung cancer (NSCLC) initially benefit from treatment with anti–epidermal growth…
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2014
2014
Abstract NG01: Blockade of EGFR and HER3 enhances PI3K/Akt antitumor activity in triple negative breast cancer
M. Scaltriti
,
Jessica J. Tao
,
+6 authors
J. Baselga
2014
Corpus ID: 71432196
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Triple negative breast cancer (TNBC) is clinically defined…
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2013
2013
Abstract P5-08-08: A human epidermal growth factor receptor 3 (HER3)-binding nanoparticle targets and kills Herceptin®-resistant human epidermal growth factor receptor 2 (HER2)-positive breast cancer
Jessica D. Sims
,
Michael Taguaim
,
Chris Hanson
,
X. Cui
,
L. Medina-Kauwe
2013
Corpus ID: 71566316
The human epidermal growth factor receptor subunit (HER2), or ErbB2, is a receptor tyrosine kinase that is amplified in…
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2013
2013
Mutations in ERBB3 drive tumorigenesis.
Cancer Discovery
2013
Corpus ID: 20458164
Somatic ERBB3 hot-spot mutations promote oncogenic signaling in a subset of human tumors.
2012
2012
Signaling by Non-Canonical Receptor Tyrosine Kinases ERBB3 and RYK
F. Shi
2012
Corpus ID: 81999152
Signaling by receptor tyrosine kinases (RTKs) typically involves binding of extracellular ligands and subsequent activation of…
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2012
2012
Abstract 3787: Pharmacokinetics and pharmacodynamics of AV-203, a humanized anti-ERBB3 antibody
K. Meetze
,
S. Tyler
,
C. Fleet
,
S. Vincent
,
James Gifford
,
J. Gyuris
2012
Corpus ID: 57246942
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL ERBB3 is widely expressed in human carcinomas, and…
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2007
2007
The importance of ERBB receptor tyrosine kinase signaling in colorectal cancer---Implications for EGFR-targeted therapies
Mingbo Yu
2007
Corpus ID: 67974798
The Apc polyps forming in the hypomorphic Egfr mice appear to grow independently of EGFR (Roberts et al., 2002). To examine the…
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