ERBB2 wt Allele

Known as: ERBB2, V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) wt Allele, HER2/neu 
Human ERBB2 wild-type allele is located in the vicinity of 17q21.1 and is approximately 29 kb in length. This allele, which encodes receptor tyrosine… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
miRNAs are small, regulatory molecules approximately 21-24 nucleotides in length. They function at the post-transcriptional level… (More)
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Highly Cited
2008
Highly Cited
2008
We explored the role of microRNAs (miRNAs) in acquiring resistance to tamoxifen, a drug successfully used to treat women with… (More)
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Highly Cited
2006
Highly Cited
2006
DNA microarray profiling studies have led to the classification of invasive breast carcinoma into luminal/estrogen receptor… (More)
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Highly Cited
2004
Highly Cited
2004
The receptor tyrosine kinase HER2 enhances tumor metastasis; however, its role in homing to metastatic organs is poorly… (More)
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Highly Cited
2003
Highly Cited
2003
Aberrations of chromosome 17 are common in breast cancer. Fluorescence in situ hybridization (FISH) enables gene or chromosome… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The PEA3 Ets transcription factor is overexpressed in the vast majority of human breast tumors and in nearly all of… (More)
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Highly Cited
1992
Highly Cited
1992
PURPOSE To evaluate the prognostic importance of immunocytochemically determined c-erbB-2 overexpression in the primary tumors of… (More)
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Highly Cited
1991
Highly Cited
1991
Drawing upon the comprehensive population-based Northern Alberta Breast Cancer Registry containing 704 patients with… (More)
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Highly Cited
1988
Highly Cited
1988
Fifty-one primary human breast tumors were analyzed for amplification of the c-erbB-2 protooncogene. Thirteen (25%) of the DNA… (More)
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Highly Cited
1988