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ERBB2 Interacting Protein, Human

Known as: Densin-180-Like Protein, Erbb2-Interacting Protein, ERBB2IP protein, human 
Protein LAP2 (1412 aa, ~158 kDa) is encoded by the human ERBIN gene. This protein plays a role in the modulation of receptor tyrosine kinase… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Significance Although knowledge about the human interactome is increasing in coverage because of the development of high… Expand
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Highly Cited
2009
Highly Cited
2009
PDZ domains have well known binding preferences for distinct C-terminal peptide motifs. For most PDZ domains, these motifs are of… Expand
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Highly Cited
2009
Highly Cited
2009
Neuregulin 1 (NRG1) plays a critical role in myelination. However, little is known about regulatory mechanisms of NRG1 signaling… Expand
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Highly Cited
2006
Highly Cited
2006
Like other protein-protein interaction domains, PDZ domains are involved in many key cellular processes. These processes often… Expand
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Highly Cited
2005
Highly Cited
2005
By constructing stably transfected cells harboring the same amount of epidermal growth factor (EGF) receptor (EGFR), but with… Expand
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Highly Cited
2003
Highly Cited
2003
The asymmetric distribution of proteins to basolateral and apical membranes is an important feature of epithelial cell polarity… Expand
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Review
2003
Review
2003
Erbin is a member of the leucine-rich repeat and PDZ domain (LAP) family. Originally cloned as an epidermal growth factor… Expand
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2002
2002
Integrity of epithelial tissues relies on the proper apical-basolateral polarity of epithelial cells. Members of the LAP (LRR and… Expand
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2001
2001
Identification of protein complexes associated with the ERBB2/HER2 receptor may help unravel the mechanisms of its activation and… Expand
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Highly Cited
2000
Highly Cited
2000
The ERBB receptors have a crucial role in morphogenesis and oncogenesis. We have identified a new PDZ protein we named ERBIN… Expand
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