ERAP1 gene

Known as: ARTS1, ERAAP, ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 
 
National Institutes of Health

Papers overview

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2014
2014
For more than 40 y, expression of HLA-B27 has been strongly associated with the chronic inflammatory disease Ankylosing… (More)
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Highly Cited
2013
Highly Cited
2013
Individuals with Behçet's disease suffer from episodic inflammation often affecting the orogenital mucosa, skin and eyes. To… (More)
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Highly Cited
2010
Highly Cited
2010
To identify new susceptibility loci for psoriasis, we undertook a genome-wide association study of 594,224 SNPs in 2,622… (More)
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Highly Cited
2009
Highly Cited
2009
A strong association between ERAP1 and ankylosing spondylitis (AS) was recently identified by the Wellcome Trust Case Control… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE The results of a recent genome-wide association study have shown that ERAP1 and IL23R are associated with ankylosing… (More)
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Highly Cited
2006
Highly Cited
2006
CD8(+) T cells respond to short peptides bound to MHC class I molecules. Although most antigenic proteins contain many sequences… (More)
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Highly Cited
2005
Highly Cited
2005
The generation of many HLA class I peptides entails a final trimming step in the endoplasmic reticulum that, in humans, is… (More)
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Highly Cited
2005
Highly Cited
2005
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an IFN-gamma-induced aminopeptidase in the endoplasmic reticulum that trims… (More)
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Review
2004
Review
2004
MHC-class-I-presented peptides are predominantly generated by the proteasome system. IFN-gamma strongly influences the processing… (More)
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Highly Cited
2002
Highly Cited
2002
Endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) appears to be specialized to produce peptides presented on class I major… (More)
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