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EPZ004777

 
National Institutes of Health

Papers overview

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2017
2017
Osteoclasts are absorptive cells that play a critical role in homeostatic bone remodeling and pathological bone resorption… Expand
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2017
2017
Incomplete epigenetic reprogramming of the genome of donor cells causes poor early and full-term developmental efficiency of… Expand
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2015
2015
Genetic alterations of the mixed-lineage leukemia (MLL) gene are commonly implicated in the development of acute leukemias. In… Expand
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2015
2015
The histone methyltransferase DOT1L, solely responsible for histone H3 lysine 79 (H3K79) methylation, is associated with gene… Expand
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Highly Cited
2013
Highly Cited
2013
The t(10;11)(p12;q23) translocation and the t(10;11)(p12;q14) translocation, which encode the MLL (mixed lineage leukemia)–AF10… Expand
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2013
2013
Genetic alterations of the mixed-lineage leukemia ( MLL ) gene are commonly identified in acute leukemias. In acute myeloid… Expand
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Highly Cited
2012
Highly Cited
2012
Selective inhibition of protein methyltransferases is a promising new approach to drug discovery. An attractive strategy towards… Expand
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2012
2012
The t(10;11)(p12;q23) translocation and the t(10;11)(p12;q14) translocation, which encode the MLL (mixed lineage leukemia)–AF10… Expand
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Highly Cited
2011
Highly Cited
2011
Mislocated enzymatic activity of DOT1L has been proposed as a driver of leukemogenesis in mixed lineage leukemia (MLL). The… Expand
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Review
2011
Review
2011
Rearrangements of the Mixed-Lineage Leukemia (MLL) gene are found in > 70% of infant leukemia, ~ 10% of adult acute myelogenous… Expand
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