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EPZ004777

National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AdenosinePhenylurea Compounds
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibition of DOT1L and PRMT5 Promotes Anti-Tumor Activity in a Human MLL Leukemia Model Induced By CRISPR/Cas9
MLL rearrangements play a crucial role in leukemogenesis. They are associated with a poor prognosis and new treatment… 
Review
2014
Review
2014
MYELOID NEOPLASIA shRNA screening identi fi es JMJD 1 C as being required for leukemia maintenance
Translocations involvingmixed lineage leukemia (MLL) gene occur frequently in acute leukemia, especially in childhood and… 
2013
2013
Myeloid Leukemia Cells With MLL partial Tandem Duplication Are Sensitive To Pharmacological Inhibition Of The H3K79 Methyltransferase DOT1L
Genetic alterations of the mixed-lineage leukemia ( MLL ) gene are commonly identified in acute leukemias. In acute myeloid… 
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