EPZ004777

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
01220112017

Papers overview

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2017
2017
Incomplete epigenetic reprogramming of the genome of donor cells causes poor early and full-term developmental efficiency of… (More)
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2015
2015
Genetic alterations of the mixed-lineage leukemia (MLL) gene are commonly implicated in the development of acute leukemias. In… (More)
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2015
2015
The histone methyltransferase DOT1L, solely responsible for histone H3 lysine 79 (H3K79) methylation, is associated with gene… (More)
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2014
2014
 
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2014
2014
Epigenetic dysregulation represents an emerging paradigm in the pathogenesis of myeloid malignancies, and the pharmacologic… (More)
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2013
2013
The t(10;11)(p12;q23) translocation and the t(10;11)(p12;q14) translocation, which encode the MLL (mixed lineage leukemia)–AF10… (More)
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Highly Cited
2012
Highly Cited
2012
Selective inhibition of protein methyltransferases is a promising new approach to drug discovery. An attractive strategy towards… (More)
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2012
2012
partnership on the discovery, development and commercialization of inhibitors of histone methyltransferases (HMTs), an emerging… (More)
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Highly Cited
2011
Highly Cited
2011
Mislocated enzymatic activity of DOT1L has been proposed as a driver of leukemogenesis in mixed lineage leukemia (MLL). The… (More)
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2011
2011
Office: Davenport Building, 25 First Street, Suite 104, Cambridge, MA 02141. Tel: (617) 475 9273, Fax: (646) 563 7109. Annual… (More)
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