Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

EPHA2 gene

Known as: EPHRIN RECEPTOR EphA2, ECK, EPITHELIAL CELL RECEPTOR PROTEIN-TYROSINE KINASE 
This gene plays a role in development and is upregulated in several breast carcinomas.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
One arising challenge in the treatment of breast cancer is the development of therapeutic resistance to trastuzumab, an antibody… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Overexpression of the receptor tyrosine kinase EPH receptor A2 (EphA2) is commonly observed in aggressive breast cancer and… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The EphA2 receptor tyrosine kinase is frequently overexpressed in many cancers, including 40% of breast cancers. Here, we show… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The EphA2 receptor tyrosine kinase is overexpressed in a variety of human cancers. We sought to characterize the role of EphA2 in… Expand
  • figure 2
  • figure 1
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The EphA2 receptor tyrosine kinase is overexpressed in many different types of human cancers where it functions as a powerful… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Elevated levels of protein tyrosine phosphorylation contribute to a malignant phenotype, although the tyrosine kinases that are… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The p53 tumor suppressor protein is mutated in more than 50% of all human cancers, which makes the study of its functions and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Epithelial cell kinase (ECK) is a receptor protein tyrosine kinase, the role of which in melanoma biology is unclear. Here we… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Protein tyrosine kinases have been implicated in tumor initiation and progression. Here we used Northern blotting to study… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
A PROTEIN ligand for the ECK1 receptor protein-tyrosine kinase has been isolated by using the extracellular domain (ECK-X) of the… Expand
Is this relevant?