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EO 5A
Known as:
EO-5A
, EO5A
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Indolequinones
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Simultaneous Quantitative Analysis of EO9 (Apaziquone) and its Conversion Products EO5a and EO9-Cl in Human and Dog Urine by High-Performance Liquid Chromatography Coupled with Electrospray Tandem…
L. Vainchtein
,
H. Rosing
,
+4 authors
J. Beijnen
2009
Corpus ID: 15400429
A sensitive and specific LC-MS/MS assay for the quantitative determination of anticancer agent EO9 and its conversion products…
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2008
2008
Enhanced resolution triple-quadrupole mass spectrometry for ultra-sensitive and quantitative analysis of the investigational anticancer agent EO9 (apaziquone) and its metabolite EO5a in human and dog…
L. Vainchtein
,
H. Rosing
,
+4 authors
J. Beijnen
Rapid Communications in Mass Spectrometry
2008
Corpus ID: 28883957
A highly sensitive and selective liquid chromatography/tandem mass spectrometric (LC/MS/MS) method was developed to quantify the…
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2007
2007
EO-9 bladder instillations: formulation selection based on stability characteristics and in vitro simulation studies.
S. C. van der Schoot
,
L. Vainchtein
,
+4 authors
B. Nuijen
International journal of pharmaceutics
2007
Corpus ID: 7972868
2006
2006
Quantitative analysis of EO9 (apaziquone) and its metabolite EO5a in human plasma by high-performance liquid chromatography under basic conditions coupled to electrospray tandem mass spectrometry.
L. Vainchtein
,
H. Rosing
,
+5 authors
J. Beijnen
Journal of Mass Spectrometry
2006
Corpus ID: 21384645
A sensitive and specific LC-MS/MS assay for the quantitative determination of EO9 and its metabolite EO5a is presented. A 200…
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1998
1998
Pharmacological and biochemical determinants of the antitumour activity of the indoloquinone EO9.
Jeffrey Cummings
,
V. Spanswick
,
Jill Gardiner
,
Alison Ritchie
,
J. F. Smyth
Biochemical Pharmacology
1998
Corpus ID: 30999054
1994
1994
Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group.
J. Verweij
,
S. Aamdal
,
J. Schellens
,
I. Koier
,
B. Lund
Oncology Research
1994
Corpus ID: 10389591
EO9 [3-hydroxy-5-aziridinyl-1-methyl-2-(1H-indole-4,7-indione)-prop-be ta- en-alpha-ol] is a new bioreductive alkylating…
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1993
1993
Sensitive isocratic high-performance liquid chromatographic determination of a novel indoloquinone cytotoxic drug (EO9) in human plasma and urine.
J. Schellens
,
W. Loos
,
J. Beijnen
,
G. Stoter
,
J. Verweij
Journal of Chromatography A
1993
Corpus ID: 22873135
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