Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ENA 713

Known as: ENA713, ENA-713, ENA 713, SDZ 
National Institutes of Health

Related topics

Related topics

2 relations
Rivastigmine tartraterivastigmine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
Paclitaxel concentrations in the brain are very low after intravenous injection. Since paclitaxel is excluded from some tumors by… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Highly Cited
1998
Highly Cited
1998
HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.
The FDA approved HIV-1 protease inhibitors, ritonavir, saquinavir, and indinavir, are very effective in inhibiting HIV-1… Expand
Highly Cited
1996
Highly Cited
1996
Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS.
This European multicenter study compares the efficacy and tolerance of the combination of pyrimethamine-clindamycin (Pyr-Cm) with… Expand
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Highly Cited
1996
Highly Cited
1996
Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay.
In order to compare the capacities of a variety of compounds to interfere with P-glycoprotein (Pgp) function, a novel assay was… Expand
Highly Cited
1996
Highly Cited
1996
Relevance of p‐glycoprotein for the enteral absorption of cyclosporin A: in vitro‐in vivo correlation
1 . The interaction of cyclosporin A (CyA) with p‐glycoprotein during intestinal uptake was investigated by a combination of in… Expand
Highly Cited
1996
Highly Cited
1996
Safety/tolerability trial of SDZ ENA 713 in patients with probable Alzheimer's disease.
SDZ ENA 713 (ENA 713) is an acetylcholinesterase inhibitor being developed as a potential treatment for Alzheimer's disease (AD… Expand
Highly Cited
1995
Highly Cited
1995
Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions.
Cyclosporins, in particular the nonimmunosuppressive derivative SDZ NIM 811, exhibit potent anti-human immunodeficiency virus… Expand
Highly Cited
1994
Highly Cited
1994
Inhibition of human immunodeficiency virus type 1 replication by SDZ NIM 811, a nonimmunosuppressive cyclosporine analog.
(Me-Ile-4)cyclosporin (SDZ NIM 811) is a 4-substituted cyclosporin which is devoid of immunosuppressive activity but retains full… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Highly Cited
1993
Highly Cited
1993
The excitatory amino acid antagonist d-CPP-ene (SDZ EAA-494) in patients with epilepsy
The amino acids L-glutamate and L-aspartate have been shown to be excitatory neurotransmitters in mammalian central nervous… Expand
Highly Cited
1991
Highly Cited
1991
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative.
Overexpression of P-glycoprotein may cause increased efflux of a variety of anticancer drugs (ACD) leading to multidrug… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE