EN1 protein, human

Known as: Engrailed 1, engrailed-1 protein, human, homeobox protein engrailed-1 protein, human 
Homeobox protein engrailed-1 (392 aa, ~40 kDa) is encoded by the human EN1 gene. This protein plays a role in both transcriptional regulation and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
024619932017

Papers overview

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Highly Cited
2004
Highly Cited
2004
Human embryonic stem (hES) cells are defined by their extensive self-renewal capacity and their potential to differentiate into… (More)
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Highly Cited
2004
Highly Cited
2004
Many of the interneuron cell types present in the adult spinal cord contribute to the circuits that control locomotion and… (More)
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2001
2001
Dorsoventral (DV) patterning of the vertebrate limb requires the function of the transcription factor Engrailed 1 (EN1) in the… (More)
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Highly Cited
2000
Highly Cited
2000
Sonic Hedgehog (Shh) is a secreted protein that controls cell fate and mitogenesis in the developing nervous system. Here we show… (More)
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Highly Cited
1999
Highly Cited
1999
During early development, multiple classes of interneurons are generated in the spinal cord including association interneurons… (More)
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Highly Cited
1997
Highly Cited
1997
The developing vertebrate mesencephalon shows a rostrocaudal gradient in the expression of a number of molecular markers and in… (More)
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Highly Cited
1996
Highly Cited
1996
A secreted signalling molecule encoded by the Wnt-1 gene is required for development of the central nervous system. In mouse… (More)
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Highly Cited
1996
Highly Cited
1996
During vertebrate limb development, positional information must be specified along three distinct axes. Although much progress… (More)
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Highly Cited
1994
Highly Cited
1994
During mouse development, the homeobox-containing gene En-1 is specifically expressed across the mid-hindbrain junction, the… (More)
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Highly Cited
1993
Highly Cited
1993
We have developed germ layer explant culture assays to study the role of mesoderm in anterior-posterior (A-P) patterning of the… (More)
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