EN1 gene

Known as: Engrailed Homeobox 1 Gene, EN1, engrailed homeobox 1 
This gene plays a role in the regulation of both gene expression and embryo morphogenesis.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The extent to which low‐frequency (minor allele frequency (MAF) between 1–5%) and rare (MAF ≤ 1%) variants contribute to complex… (More)
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2013
2013
Mesodiencephalic dopaminergic (mdDA) neurons control locomotion and emotion and are affected in multiple psychiatric and… (More)
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2011
2011
The transcription factors PITX3 and Engrailed 1 (EN1), among others, have been shown to play a crucial role in the maturation and… (More)
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Highly Cited
2005
Highly Cited
2005
How dopamine (DA) neuronal subtypes are specified remains unknown. In this study we show a robust generation of functional DA… (More)
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Highly Cited
2003
Highly Cited
2003
Idiopathic congenital central hypoventilation syndrome (CCHS) has been linked to autonomic nervous system dysregulation and/or… (More)
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Highly Cited
2001
Highly Cited
2001
Dorsoventral (DV) patterning of the vertebrate limb requires the function of the transcription factor Engrailed 1 (EN1) in the… (More)
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Highly Cited
2000
Highly Cited
2000
Proximal-distal outgrowth of the vertebrate limb bud is regulated by the apical ectodermal ridge (AER), which forms at an… (More)
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Highly Cited
1997
Highly Cited
1997
Members of the PAX family of transcription factors are candidates for controlling cell identity in the spinal cord. We have… (More)
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Highly Cited
1996
Highly Cited
1996
Motor neuron differentiation is accompanied by the expression of a LIM homeodomain transcription factor, Islet1 (ISL1). To assess… (More)
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1994
1994
The structure of the Drosophila engrailed homeodomain has been solved by molecular replacement and refined to an R-factor of 19.7… (More)
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