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EL625
A phosphorothioate oligonucleotide harboring nucleotide sequences complementary to tumor suppressor p53 mRNA. EL625 hybridizes with p53 mRNA…
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National Institutes of Health
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OL(1)p53
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2005
2005
Phase II study of EL625, a p53 antisense oligonucleotide, and chemotherapy in refractory and relapsed acute myelogenous leukemia (AML)
E. Freireich
,
H. Kantarjian
,
+7 authors
J. Cortes
2005
Corpus ID: 73822014
6617 EL625, an antisense phosphorothioate, induces RNase H dependent cleavage of p53 transcripts resulting in loss of p53…
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