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EIF2B4 protein, human
Known as:
EIF2B4
, Eukaryotic Translation Initiation Factor 2B, Delta
, EIF2B Delta
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Translation initiation factor eIF-2B subunit delta (523 aa, ~58 kDa) is encoded by the human EIF2B4 gene. This protein plays a role in both guanine…
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National Institutes of Health
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Related topics
Related topics
16 relations
EIF2B1 gene
EIF2B1 protein, human
EIF2B2 gene
EIF2B3 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Structural insights into ISRIB, a memory‐enhancing inhibitor of the integrated stress response
A. Anand
,
P. Walter
The FEBS Journal
2020
Corpus ID: 202760629
The integrated stress response (ISR) regulates protein synthesis under conditions of stress. Phosphorylation of translation…
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2016
2016
rAed a 4: A New 67-kDa Aedes aegypti Mosquito Salivary Allergen for the Diagnosis of Mosquito Allergy
Zhikang Peng
,
Liao Caihe
,
A. Beckett
,
Q. Guan
,
A. James
,
F. Simons
International Archives of Allergy and Immunology
2016
Corpus ID: 11185467
Background: Accurate diagnosis of mosquito allergy has been hampered by the laborious task of obtaining mosquito salivary…
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Highly Cited
2015
Highly Cited
2015
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
C. Sidrauski
,
J. Tsai
,
+14 authors
P. Walter
eLife
2015
Corpus ID: 18249953
The general translation initiation factor eIF2 is a major translational control point. Multiple signaling pathways in the…
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Highly Cited
2013
Highly Cited
2013
eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation
Martin D. Jennings
,
Yu Zhou
,
Sarah S. Mohammad-Qureshi
,
David Bennett
,
G. Pavitt
Genes & Development
2013
Corpus ID: 24649334
Protein synthesis factor eIF2 delivers initiator tRNA to the ribosome. Two proteins regulate its G-protein cycle: eIF5 has both…
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2008
2008
Discrimination between stable and dynamic components of protein complexes by means of quantitative proteomics
K. Kito
,
N. Kawaguchi
,
S. Okada
,
Takashi Ito
Proteomics
2008
Corpus ID: 31485132
To discriminate between stable and dynamic protein–protein interactions, we propose a strategy in which cells with and without…
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Highly Cited
2007
Highly Cited
2007
A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes.
K. Kito
,
K. Ota
,
Tomoko Fujita
,
Takashi Ito
Journal of Proteome Research
2007
Corpus ID: 23282458
Quantitative description of protein interactions is crucial to understand and model molecular systems regulating various cellular…
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1998
1998
Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cells.
J. Fabian
,
S. Kimball
,
L. Jefferson
Protein Expression and Purification
1998
Corpus ID: 22209847
Eukaryotic initiation factor eIF2B plays a key role in the regulation of protein synthesis through its ability to catalyze the…
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