EIF2AK4 gene

Known as: GENERAL CONTROL NONDEREPRESSIBLE 2, KIAA1338, EIF2AK4 
This gene plays a role in protein phosphorylation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0102019842018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Enhanced fibroblast growth factor 21 (FGF21) production and circulation has been linked to the metabolic adaptation to starvation… (More)
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Highly Cited
2005
Highly Cited
2005
Indoleamine 2,3 dioxygenase (IDO) catabolizes the amino acid tryptophan. IDO-expressing immunoregulatory dendritic cells (DCs… (More)
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Highly Cited
2005
Highly Cited
2005
Exposure of cells to endoplasmic reticulum (ER) stress leads to activation of PKR-like ER kinase (PERK), eukaryotic translation… (More)
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Highly Cited
2004
Highly Cited
2004
In eukaryotic cells, amino acid depletion reduces translation by a mechanism involving phosphorylation of eukaryotic initiation… (More)
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Highly Cited
2003
Highly Cited
2003
Yeast protein kinase GCN2 stimulates the translation of transcriptional activator GCN4 by phosphorylating eIF2alpha in response… (More)
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Highly Cited
2000
Highly Cited
2000
A family of protein kinases regulates translation in response to different cellular stresses by phosphorylation of the alpha… (More)
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Highly Cited
1995
Highly Cited
1995
Protein kinase GCN2 is a multidomain protein that contains a region homologous to histidyl-tRNA synthetases juxtaposed to the… (More)
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Highly Cited
1992
Highly Cited
1992
We show that phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2) by the protein kinase… (More)
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1992
1992
The protein kinase GCN2 stimulates expression of the yeast transcriptional activator GCN4 at the translational level by… (More)
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Highly Cited
1989
Highly Cited
1989
The GCN2 protein of Saccharomyces cerevisiae stimulates the expression of amino acid biosynthetic genes under conditions of amino… (More)
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