EIF2AK3 wt Allele

Known as: PEK, PERK, Eukaryotic Translation Initiation Factor 2-Alpha Kinase 3 wt Allele 
Human EIF2AK3 wild-type allele is located in the vicinity of 2p12 and is approximately 71 kb in length. This allele, which encodes eukaryotic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The unfolded protein response (UPR) is a signal transduction pathway that coordinates cellular adaptation to microenvironmental… (More)
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Highly Cited
2011
Highly Cited
2011
Disturbance of calcium homeostasis and accumulation of misfolded proteins in the endoplasmic reticulum (ER) are considered… (More)
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Highly Cited
2006
Highly Cited
2006
Regulated phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) by the endoplasmic… (More)
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Highly Cited
2003
Highly Cited
2003
Nuclear factor kappaB (NF-kappaB) serves to coordinate the transcription of genes in response to diverse environmental stresses… (More)
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Highly Cited
2002
Highly Cited
2002
Hypoxia profoundly influences tumor development and response to therapy. While progress has been made in identifying individual… (More)
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Review
2002
Review
2002
Eukaryotic cells express a family of eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinases (eg, PKR, PERK-PEK… (More)
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Highly Cited
2001
Highly Cited
2001
Phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) on serine 51 integrates general… (More)
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Highly Cited
2000
Highly Cited
2000
In response to different cellular stresses, a family of protein kinases regulates translation by phosphorylation of the alpha… (More)
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Highly Cited
1998
Highly Cited
1998
In response to various environmental stresses, eukaryotic cells down-regulate protein synthesis by phosphorylation of the alpha… (More)
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Highly Cited
1998
Highly Cited
1998
In his van Fraassen argues that Inference to the Best Explanation is incoherent in the sense that adopting it as a rule for… (More)
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