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EBC-46

National Institutes of Health

Papers overview

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2020
2020
Abstract Objective To evaluate the efficacy and safety of tigilanol tiglate (TT) for local intratumoral treatment of mast cell… Expand
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2020
2020
Epoxy-tiglianes are a novel class of diterpene esters. The prototype epoxy-tigliane, EBC-46 (tigilanol tiglate), possesses potent… Expand
2019
2019
Mast cell tumor (MCT) is the most common cutaneous neoplasm in dogs and wide surgical resection is the current first-line… Expand
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2019
2019
Background Tigilanol tiglate, a short-chain diterpene ester, is being developed as intratumoral treatment of a broad range of… Expand
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Review
2019
Review
2019
Macrocyclic diterpenoids produced by plants of the Euphorbiaceae family are of considerable interest due to their high structural… Expand
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2018
2018
SummaryThe five-year survival rate for patients with head and neck squamous cell carcinoma (HNSCC) has remained at ~50% for the… Expand
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2016
2016
BackgroundFontainea picrosperma, a subcanopy tree endemic to the rainforests of northeastern Australia, is of medicinal… Expand
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2015
2015
Background: EBC-46 is a novel protein kinase C (PKC) activator being developed for intratumoral treatment of cutaneous and… Expand
Highly Cited
2014
Highly Cited
2014
Intra-lesional chemotherapy for treatment of cutaneous malignancies has been used for many decades, allowing higher local drug… Expand
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