E2F4 gene

Known as: E2F TRANSCRIPTION FACTOR 4, E2F-4, E2F4 
This gene plays a role in tumor suppressor-dependent transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Cell cycle progression is dependent on two major waves of gene expression. Early cell cycle gene expression occurs during G1/S to… (More)
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Highly Cited
2011
Highly Cited
2011
The E2F family of transcription factors has important roles in cell cycle progression. E2F4 is an E2F family member that has been… (More)
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Highly Cited
2007
Highly Cited
2007
The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not… (More)
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Highly Cited
2007
Highly Cited
2007
Using ChIP-chip assays (employing ENCODE arrays and core promoter arrays), we examined the binding patterns of three members of… (More)
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Highly Cited
2007
Highly Cited
2007
We and others have shown that the dysregulation of DNA repair pathways can contribute to the phenomenon of hypoxia-induced… (More)
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Highly Cited
2007
Highly Cited
2007
Here we report the identification of the LIN complex (LINC), a human multiprotein complex that is required for transcriptional… (More)
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Highly Cited
2004
Highly Cited
2004
Using genome-wide analysis of transcription factor occupancy, we investigated the mechanisms underlying three mammalian growth… (More)
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Highly Cited
2000
Highly Cited
2000
The retinoblastoma protein (pRB) plays a key role in the control of normal development and proliferation through the regulation… (More)
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Highly Cited
2000
Highly Cited
2000
E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual… (More)
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Highly Cited
2000
Highly Cited
2000
We have generated mice deficient in E2F4 activity, the major form of E2F in many cell types. Analysis of newborn pups deficient… (More)
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