FAQ

E 6080

Known as: E-6080, E6080 
 

Topic mentions per year

Topic mentions per year

1990-1994
01219901994

Related topics

Related topics

1 relation

Broader (1)

Thiazoles

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
E 6080
Thiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Inhibition of leukotriene C4 and B4 release by human eosinophils with the new 5-lipoxygenase inhibitor 6-hydroxy-2(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride.
Eosinophils generate and release leukotrienes C4 and B4 (LTC4, LTB4) and platelet activating factor (PAF), all of which have the… (More)
Is this relevant?
1994
1994
Interactions between cytokines and eicosanoids: a study using human peritoneal macrophages.
To examine the interactions between the main pro-inflammatory cytokines and eicosanoids produced by human inflammatory cells… (More)
Is this relevant?
1994
1994
Phorbol ester-induced dermal inflammation in mice: evaluation of inhibitors of 5-lipoxygenase and antagonists of leukotriene B4 receptor.
In the present investigation, the effects of selective inhibitors of 5-lipoxygenase (5-LO), zileuton and TZI-41127, E-6080, AA… (More)
Is this relevant?
1993
1993
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
To define the role of platelet activating factor (PAF) in allergic rhinitis, we examined the effects of anti-PAF agents (WEB2086… (More)
Is this relevant?
1993
1993
Inhibition of IgE-mediated leukotriene generation and bronchoconstriction in primates with a new 5-lipoxygenase inhibitor, E6080.
The inhibitory effects of a novel compound, 6-hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride… (More)
Is this relevant?
1992
1992
Species difference and tissue distribution of uridine diphosphate-glucuronyltransferase activities toward E6080, 1-naphthol and 4-hydroxybiphenyl.
The apparent in vitro kinetic constants of uridine diphosphate-glucuronyltransferase (UDP-GT) activities towards E6080, 1… (More)
Is this relevant?
1992
1992
Effects of the new 5-lipoxygenase inhibitor E6080 on leukotriene release in vitro.
Fundamental studies were conducted to examine the release of histamine and leukotriene (LT) C4 from lung fragments of guinea pigs… (More)
Is this relevant?
1991
1991
Determination of plasma leukotrienes in antigen-induced bronchoconstrictive guinea pigs.
Convenient extraction and radioimmunoassay methods for measurement of leukotrienes C4 and D4 (LTC4 and LTD4) in biological fluids… (More)
Is this relevant?
1991
1991
Effect of a novel 5-lipoxygenase inhibitor, E6080 on bronchospasm, airway cellular infiltration and leukotriene production in guinea pigs.
6-Hydroxy-2-(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride (E6080), an orally active and selective 5… (More)
Is this relevant?
1990
1990
Involvement of leukotriene C4 in PAF-induced death in mice.
The role of leukotrienes (LTs) in the pathogenesis of platelet-activating factor (PAF)-induced death in mice was reinvestigated… (More)
Is this relevant?