E 4031

Known as: E-4031, Methanesulfonamide, N-(4-((1-(2-(6-methyl-2-pyridinyl)ethyl)-4-piperidinyl)carbonyl)phenyl)- 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Effects of bepridil on the depolarization-activated outward K(+) currents (I(out)) in rat atrial myocytes and the human cardiac K… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
A novel potassium channel gene has been cloned, characterized, and associated with cardiac arrhythmia. The gene encodes MinK… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
1999
1999
Effects of block of the rapid delayed rectifier K+ current (IK,r) by E-4031 on the electrical activity of small ball-like tissue… (More)
Is this relevant?
1997
1997
Rectification of HERG is due to a rapid inactivation process that has been labeled C-type inactivation and is believed to be due… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
We recently reported that mutations in HERG, a potassium channel gene, cause long QT syndrome. Heterologous expression of HERG in… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Previous voltage-clamp studies have suggested that the delayed rectifier current (IK) is small or absent in the human ventricle… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Recent studies have described regional differences in the electrophysiology and pharmacology of ventricular myocardium in canine… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
The mechanism by which isoproterenol (ISO) prevents the prolongation of action potential duration (APD) and refractory period (RP… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1990
Highly Cited
1990
An envelope of tails test was used to show that the delayed rectifier K+ current (IK) of guinea pig ventricular myocytes results… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
1990
1990
Block of the delayed rectifier potassium current, IK, by the class IC antiarrhythmic agent, flecainide, and by the novel… (More)
  • figure 1
  • figure 2
Is this relevant?