Drug or chemical Tissue Distribution

Known as: Tissue Distribution, Distribution, Tissue, Distributions, Tissue 
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
BACKGROUND The cJun-N-terminal-kinase (JNK) plays a central role in the cell stress response, with outcomes ranging from cell… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Vitamin D receptors have a broad tissue distribution that includes vascular smooth muscle, endothelium, and… (More)
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Highly Cited
2003
Highly Cited
2003
Chronic viral infections often result in ineffective CD8 T-cell responses due to functional exhaustion or physical deletion of… (More)
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Highly Cited
2002
Highly Cited
2002
Ghrelin is a novel growth hormone-releasing peptide, originally identified in the rat stomach as the endogenous ligand for the… (More)
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Highly Cited
2001
Highly Cited
2001
High expression of the Breast Cancer Resistance Protein (BCRP) gene has been shown to be involved in resistance to… (More)
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Highly Cited
1998
Highly Cited
1998
Estrogens influence the differentiation and maintenance of reproductive tissues and affect lipid metabolism and bone remodeling… (More)
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Highly Cited
1997
Highly Cited
1997
The rat estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal ligand binding domain… (More)
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Highly Cited
1996
Highly Cited
1996
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily that can be activated… (More)
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Highly Cited
1996
Highly Cited
1996
Increased activity of lipoprotein lipase (LPL) may explain the hypotriglyceridemic effects of fibrates, thiazolidinediones and… (More)
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Highly Cited
1986
Highly Cited
1986
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated… (More)
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