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Drug Screening Assays, Antitumor

Known as: Cancer Drug Tests, Antitumor Drug Screening Assay, Drug Test, Cancer 
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Drug development is a lengthy and costly process that proceeds through several stages from target identification to lead… 
Highly Cited
2006
Highly Cited
2006
CONTEXT Adverse drug events are common and often preventable causes of medical injuries. However, timely, nationally… 
Review
1998
Review
1998
The cytochrome P450s (CYPs) constitute a superfamily of isoforms that play an important role in the oxidative metabolism of drugs… 
Highly Cited
1995
Highly Cited
1995
A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is… 
Review
1995
Review
1995
During 1985–1990 the U.S. National Cancer Institute (NCI) phased out its murine leukemia P388 anticancer drug screening program… 
Review
1995
Review
1995
OBJECTIVES To assess incidence and preventability of adverse drug events (ADEs) and potential ADEs. To analyze preventable events… 
Review
1992
Review
1992
THE immunosuppressive drugs cyclosporin A (CsA) and FKS06 both interfere with a Ca2+-sensitive T-cell signal transduction… 
Highly Cited
1991
Highly Cited
1991
We describe here the development and implementation of a pilot-scale, in vitro, anticancer drug screen utilizing a panel of 60…