Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 217,467,619 papers from all fields of science
Search
Sign In
Create Free Account
Drug Screening Assays, Antitumor
Known as:
Cancer Drug Tests
, Antitumor Drug Screening Assay
, Drug Test, Cancer
Expand
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Tumor Cells, Cultured
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
Sigrid A. Langhans
Frontiers in Pharmacology
2018
Corpus ID: 21597318
Drug development is a lengthy and costly process that proceeds through several stages from target identification to lead…
Expand
Review
2007
Review
2007
Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials
R. Christensen
,
P. K. Kristensen
,
E. Bartels
,
H. Bliddal
,
A. Astrup
The Lancet
2007
Corpus ID: 32416126
Highly Cited
2006
Highly Cited
2006
National surveillance of emergency department visits for outpatient adverse drug events.
D. Budnitz
,
D. Pollock
,
Kelly N. Weidenbach
,
A. Mendelsohn
,
Thomas J. Schroeder
,
J. Annest
Journal of the American Medical Association (JAMA…
2006
Corpus ID: 24055415
CONTEXT Adverse drug events are common and often preventable causes of medical injuries. However, timely, nationally…
Expand
Review
1998
Review
1998
Inhibition and Induction of Cytochrome P450 and the Clinical Implications
J. Lin
,
A. Y. Lu
Clinical Pharmacokinetics
1998
Corpus ID: 11393482
The cytochrome P450s (CYPs) constitute a superfamily of isoforms that play an important role in the oxidative metabolism of drugs…
Expand
Highly Cited
1995
Highly Cited
1995
A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
G. Amidon
,
H. Lennernäs
,
V. Shah
,
J. Crison
Pharmaceutical Research
1995
Corpus ID: 21085622
A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is…
Expand
Review
1995
Review
1995
Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen
M. Boyd
,
K. Paull
1995
Corpus ID: 34828430
During 1985–1990 the U.S. National Cancer Institute (NCI) phased out its murine leukemia P388 anticancer drug screening program…
Expand
Review
1995
Review
1995
Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group.
D. Bates
,
D. Cullen
,
+7 authors
R. Hallisey
Journal of the American Medical Association (JAMA…
1995
Corpus ID: 42404093
OBJECTIVES To assess incidence and preventability of adverse drug events (ADEs) and potential ADEs. To analyze preventable events…
Expand
Review
1994
Review
1994
Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance.
J. Houston
Biochemical Pharmacology
1994
Corpus ID: 35538705
Review
1992
Review
1992
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
N. Clipstone
,
G. Crabtree
Nature
1992
Corpus ID: 4363653
THE immunosuppressive drugs cyclosporin A (CsA) and FKS06 both interfere with a Ca2+-sensitive T-cell signal transduction…
Expand
Highly Cited
1991
Highly Cited
1991
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.
A. Monks
,
D. Scudiero
,
+11 authors
M. Boyd
Journal of the National Cancer Institute
1991
Corpus ID: 8698400
We describe here the development and implementation of a pilot-scale, in vitro, anticancer drug screen utilizing a panel of 60…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE