Drug Development, Preclinical

Known as: Drug Testing/Development, Preclinical 
Drug development activites focused on preclinical trials and testing.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
01219902017

Papers overview

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Review
2018
Review
2018
OBJECTIVES In pharmaceutical drug development, preclinical tests in animal models are essential to demonstrate whether the new… (More)
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2017
2017
Sodium 4-phenylbutyrate (PB) is clinically used as a drug for treating urea cycle disorders. Recent research has shown that PB… (More)
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2015
2015
In the process of drug development, preclinical safety studies are to be performed that require the analysis of the compound at… (More)
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Review
2015
Review
2015
AIM This paper describes how in a problem-based learning (PBL) medical curriculum, having identified the learning outcomes… (More)
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Review
2011
Review
2011
Advances in clinical and translation science are facilitated by building on prior knowledge gained through experimentation and… (More)
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Review
2008
Review
2008
Variability of drug metabolism, especially that of the most important phase I enzymes or cytochrome P450 (CYP) enzymes, is an… (More)
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2008
2008
Chemokine CC motif receptor (CCR) 5 is a major drug target for both inflammation and virology indications. The primary function… (More)
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2007
2007
In the process of drug development, preclinical testing using experimental animals is an important aspect, for verification of… (More)
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Review
1990
Review
1990
The aged are now viewed as a special population for the purposes of drug development. This has produced challenges for the… (More)
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