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DprE1 protein, Mycobacterium tuberculosis

Known as: decaprenyl-phosphoryl-beta-D-ribofuranose oxidoreductase DprE1, M tuberculosis, decaprenylphosphoryl-beta-D-ribose2'-epimerase, Mycobacterium tuberculosis 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Alcohol OxidoreductasesBacterial Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Determinants of the Inhibition of DprE 1 and CYP 2 C 9 by Antitubercular Thiophenes
Mycobacterium tuberculosis (Mtb) DprE1, an essential isomerase for the biosynthesis of the mycobacterial cell wall, is a… Expand
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Review
2016
Review
2016
New and Old Hot Drug Targets in Tuberculosis.
Tuberculosis is an infectious disease caused by the bacillus Mycobacterium tuberculosis. The World Health Organization publishes… Expand
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2013
2013
Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
We report 1,4-azaindoles as a new inhibitor class that kills Mycobacterium tuberculosis in vitro and demonstrates efficacy in… Expand
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Highly Cited
2013
Highly Cited
2013
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
Significance The global problem of TB has worsened in recent years with the emergence of drug-resistant organisms, and new drugs… Expand
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