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DprE1 protein, Mycobacterium tuberculosis

Known as: decaprenyl-phosphoryl-beta-D-ribofuranose oxidoreductase DprE1, M tuberculosis, decaprenylphosphoryl-beta-D-ribose2'-epimerase, Mycobacterium tuberculosis 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Alcohol OxidoreductasesBacterial Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Determinants of the Inhibition of DprE 1 and CYP 2 C 9 by Antitubercular Thiophenes
Mycobacterium tuberculosis (Mtb) DprE1, an essential isomerase for the biosynthesis of the mycobacterial cell wall, is a… 
Review
2016
Review
2016
New and Old Hot Drug Targets in Tuberculosis.
Tuberculosis is an infectious disease caused by the bacillus Mycobacterium tuberculosis. The World Health Organization publishes… 
Highly Cited
2013
Highly Cited
2013
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
Significance The global problem of TB has worsened in recent years with the emergence of drug-resistant organisms, and new drugs… 
Highly Cited
2013
Highly Cited
2013
Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
We report 1,4-azaindoles as a new inhibitor class that kills Mycobacterium tuberculosis in vitro and demonstrates efficacy in… 
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