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Donor Regulatory T-lymphocytes

Known as: Donor CD4+CD25+FoxP3+ T Cells 
Donor-derived regulatory T-cells (Tregs), with potential immunomodulating activity. Tregs are a subset of CD4+ T cells that express high levels of… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Understanding the role of the kynurenine pathway in human breast cancer immunobiology
Breast cancer (BrCa) is the leading cause of cancer related death in women. While current diagnostic modalities provide… Expand
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2016
2016
Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model.
Recent studies have demonstrated that regulatory T cells (Tregs) are recruited to tumor sites where they can suppress antitumor… Expand
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2015
2015
원저 : 건선환자의 말초혈액 내 CD4+CD25+Foxp3+ Regulatory T 세포와 CD4+CD25.Foxp3+ T 세포 수에 관한 연구
Background: Regulatory T cells (Treg) are able to inhibit the immunological response and maintain cutaneous immunological… Expand
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2010
2010
Dual roles of CD4+CD25+Foxp3+ Tregs in regulating Th17 cells and promoting host resistance to Candida albicans
 
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Highly Cited
2010
Highly Cited
2010
Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.
PURPOSE Blockade of CTL-associated antigen-4 (CTLA-4), an inhibitory immunomodulatory molecule on T cells, has been shown to… Expand
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Highly Cited
2008
Highly Cited
2008
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
The molecular mechanisms directing the development of 'natural' CD4+CD25+Foxp3+ regulatory T cells (Treg cells) in the thymus are… Expand
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Review
2008
Review
2008
Regulatory T cells and the induction of IL-17
T helper (Th)17 cells have been shown to play a role in the pathogenesis of inflammatory and autoimmune diseases including… Expand
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2007
2007
Regulatorische CD4+CD25+Foxp3+ T-Lymphozyten verhindern das sekundäre Infarktwachstum über einen Interleukin-10 abhängigen Signalweg
 
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Highly Cited
2007
Highly Cited
2007
Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells
BackgroundCD4+CD25+ T regulatory cells (Tregs) play an important role in regulating immune responses, and in influencing human… Expand
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Highly Cited
2006
Highly Cited
2006
Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells.
Regulatory T cells (Tregs) have been implicated as key players in immune tolerance as well as suppression of antitumor responses… Expand
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