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Docetaxel-loaded Nanopharmaceutical CRLX301

Known as: CRLX301 
A nanoparticle-based formulation containing the poorly water-soluble, second-generation taxane analog docetaxel, with antineoplastic activity. Upon… Expand
National Institutes of Health

Papers overview

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2017
2017
Cerulean Pharma Inc.9s Dynamic Tumor Targeting™ Platform creates nanoparticle-drug conjugates (NDCs) designed to significantly… Expand
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2016
2016
2526Background: CRLX301 is an investigational NDC with DOC covalently conjugated to a cyclodextrin-polyethylene glycol co-polymer… Expand
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2016
2016
Introduction. Nanoparticles (NPs) provide many advantages over small molecule drugs, such as greater solubility, increased… Expand
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2012
2012
Docetaxel is one of the most commonly prescribed anticancer agents. While efficacious, the therapeutic benefits of docetaxel are… Expand
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Highly Cited
2009
Highly Cited
2009
In this paper we examine the effect of rotation rate, mixing angle, and cohesion on the powder residence time and the content… Expand
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