Disintegrin Domain

It is an integrin binding domain originally identified in ADAM family proteins. (NCI)
National Institutes of Health

Papers overview

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2006
2006
OBJECTIVE To study the expression and function of the brain-specific proteinase deficient disintegrins, ADAM11 and ADAM22 (a… (More)
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2005
2005
The ADAM (a disintegrin and metalloprotease) family of proteins possess both proteolytic and adhesive domains. We have… (More)
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2004
2004
Metargidin, a transmembrane protein of the adamalysin family, and integrins, e.g., alpha5beta1 and alphav, are preferentially… (More)
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Highly Cited
2003
Highly Cited
2003
ADAMTS13 consists of a reprolysin-type metalloprotease domain followed by a disintegrin domain, a thrombospondin type 1 motif… (More)
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Highly Cited
2002
Highly Cited
2002
ADAMs (a disintegrin and metalloprotease domains) are metalloprotease and disintegrin domain-containing transmembrane… (More)
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Highly Cited
2001
Highly Cited
2001
ADAM 3 is a sperm surface glycoprotein that has been implicated in sperm-egg adhesion. Because little is known about the adhesive… (More)
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Highly Cited
1997
Highly Cited
1997
Sperm-egg plasma membrane fusion is preceded by sperm adhesion to the egg plasma membrane. Cell-cell adhesion frequently involves… (More)
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Highly Cited
1996
Highly Cited
1996
Cellular disintegrins are a family of membrane-anchored proteins with structural homology to snake venom metalloproteases and… (More)
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Highly Cited
1996
Highly Cited
1996
Cellular disintegrins are a family of proteins that are related to snake venom integrin ligands and metalloproteases. We have… (More)
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Review
1992
Review
1992
Disintegrins are soluble integrin ligands from snake venoms that disrupt cell-matrix interactions. Recently, the nuclear magnetic… (More)
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