Disabled Homolog 2 Protein

Known as: Mitogen-Responsive Phosphoprotein, Disabled Homolog 2, Mitogen-Responsive Phosphoprotein, Differentially Expressed in Ovarian Cancer 2 
Disabled homolog 2 (770 aa, ~82 kDa) is encoded by the human DAB2 gene. This protein plays a role in signal transduction.
National Institutes of Health

Papers overview

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2012
2012
Bone morphogenetic proteins (BMPs) have diverse functions during development in vertebrates. We have recently shown that BMP2… (More)
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Highly Cited
2012
Highly Cited
2012
MicroRNAs (miRNAs) play important roles in tumorigenesis by regulating oncogenes and tumor-suppressor genes. In this study, miR… (More)
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2010
2010
The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During… (More)
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Highly Cited
2009
Highly Cited
2009
Focal adhesion disassembly is regulated by microtubules (MTs) through an unknown mechanism that involves dynamin. To test whether… (More)
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Highly Cited
2006
Highly Cited
2006
Clathrin-mediated endocytosis requires cargo-specific adaptor proteins that recognize specific receptors and recruit them into… (More)
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Highly Cited
2002
Highly Cited
2002
The signal transduction adapter protein Disabled-2 (Dab2) is one of the two mammalian orthologs of the Drosophila Disabled. The… (More)
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Highly Cited
2002
Highly Cited
2002
No clear patterns in molecular changes underlying the malignant processes in lung cancer of different histological types have… (More)
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Highly Cited
2001
Highly Cited
2001
Disabled-2 (Dab2) is a widely expressed relative of Disabled-1, a neuron-specific signal-transduction protein that binds to and… (More)
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1998
1998
Disabled-2 (Dab2), a mammalian structural homolog of Drosophila Disabled (Dab), is a mitogen-responsive phosphoprotein. It has… (More)
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Highly Cited
1997
Highly Cited
1997
DOC2 proteins constitute a novel protein family that may function in secretion and contain a double C2 domain. We have cloned and… (More)
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