Dimethadione

Known as: 5,5-Dimethyl-2,4-oxazolidinedione, 2,4-Oxazolidinedione, 5,5-dimethyl-, 5,5-Dimethyloxazolidine-2,4-dione 
An anticonvulsant that is the active metabolite of TRIMETHADIONE.
National Institutes of Health

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9 relations

Broader (1)

Anticonvulsants
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (1)

dichlozoline

Papers overview

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1996
1996
Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: Ethosuximide, trimethadione, and dimethadione
Spontaneous generalized epileptiform discharges were elicited in rodent thalamocortical slices by perfusion with a medium… (More)
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1989
1989
Maintenance of Intracellular pH and Acid Tolerance in Rhizobium meliloti.
The development and function of the Rhizobium meliloti-Medicago sp. symbiosis are sensitive to soil acidity. Physiological… (More)
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Highly Cited
1989
Highly Cited
1989
Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons.
The mechanism by which ethosuximide reduces thalamic low-threshold calcium current (LTCC) was analyzed using voltage-clamp… (More)
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1985
1985
Intracellular pH transients in rainbow trout tissues measured by dimethadione distribution.
Intracellular pH transients in response to PCO2 changes were measured in vitro with the weak acid dimethadione (DMO) in gas… (More)
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1984
1984
Extracellular Na+ and initiation of DNA synthesis: role of intracellular pH and K+
Initiation of DNA synthesis in confluent quiescent 3T3 cell cultures stimulated by epidermal growth factor (EGF), vasopressin… (More)
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1982
1982
Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.
Addition of Na+ to Na+-depleted Swiss 3T3 cells causes a rapid and dramatic increase in intracellular pH, as monitored by uptake… (More)
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Highly Cited
1981
Highly Cited
1981
The stimulus-secretion coupling of glucose-induced insulin release
When isolated rat islets were exposed to glucose, the concentrations of NADH and NADPH, and the NADH/NAD+ and NADPH/NADP+ ratios… (More)
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1979
1979
Correlation of Adenosine Triphosphate Levels in Chara corallina with the Activity of the Electrogenic Pump.
The effect of a number of inhibitors on the ATP level in single cells of Chara corallina has been measured using the luciferin… (More)
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1979
1979
The stimulus-secretion coupling of glucose-induced insulin release. XXXV. The links between metabolic and cationic events.
When isolated rat islets were exposed to glucose, the concentrations of NADH and NADPH, and the NADH/NAD+ and NADPH/NADP+ ratios… (More)
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1978
1978
Dimethadione-induced fetotoxicity in rats.
The fetotoxic potential of dimethadione was studied in rats given single daily oral dosages of 0, 54, 433 or 541 mg/kg on days 1… (More)
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