Differential In-Gel Electrophoresis

Known as: DIGE, Difference Gel Electrophoresis 
A form of gel electrophoresis where up to three different protein samples can be labeled with fluorescent dyes prior to two-dimensional… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
In quantitative proteomics, the false discovery rate (FDR) can be defined as the number of false positives within statistically… (More)
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Review
2005
Review
2005
Two-dimensional (2D) gel electrophoresis is a powerful technique enabling simultaneous visualization of relatively large portions… (More)
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Highly Cited
2005
Highly Cited
2005
The identification of specific protein markers for colorectal cancer would provide the basis for early diagnosis and detection… (More)
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Highly Cited
2004
Highly Cited
2004
Two-dimensional difference gel electrophoresis (2-D DIGE) coupled with mass spectrometry (MS) was used to investigate tumor… (More)
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Highly Cited
2004
Highly Cited
2004
2D polyacrylamide gel electrophoresis has been the traditional workhorse of proteomics, allowing for the resolution of several… (More)
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Highly Cited
2003
Highly Cited
2003
The comparison of two-dimensional (2-D) gel images from different samples is an established method used to study differences in… (More)
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Highly Cited
2002
Highly Cited
2002
The reproducibility of conventional two-dimensional (2D) gel electrophoresis can be improved using differential in-gel… (More)
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Highly Cited
2002
Highly Cited
2002
The technique of fluorescent two-dimensional (2D) difference gel electrophoresis for differential protein expression analysis has… (More)
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Highly Cited
2001
Highly Cited
2001
Fluorescence two-dimensional differential gel electrophoresis (2-D DIGE*) is a new development in protein detection for two… (More)
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Highly Cited
1997
Highly Cited
1997
We describe a modification of two-dimensional (2-D) polyacrylamide gel electrophoresis that requires only a single gel to… (More)
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