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Differential In-Gel Electrophoresis

Known as: DIGE, Difference Gel Electrophoresis 
A form of gel electrophoresis where up to three different protein samples can be labeled with fluorescent dyes prior to two-dimensional… 
National Institutes of Health

Papers overview

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2014
2014
Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex.
2011
2011
Comparative proteomic profiles of the soybean (Glycine max) root apex and differentiated root zone
The root apical meristem (RAM) is responsible for the growth of the plant root system. Because of the importance of root… 
Highly Cited
2009
Highly Cited
2009
2‐D DIGE analysis of the proteome of extracts from peanut variants reveals striking differences in major allergen contents
Over the last decade, an increasing prevalence of peanut allergies was observed worldwide. Peanuts are meanwhile categorized… 
2008
2008
Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus-associated Bladder Dysfunction *S
Protein expression profiles in rat bladder smooth muscle were compared between animal models of streptozotocin-induced diabetes… 
Highly Cited
2008
Highly Cited
2008
Proteomic Analysis of Pancreatic Ductal Adenocarcinoma Compared with Normal Adjacent Pancreatic Tissue and Pancreatic Benign Cystadenoma
Background: Dual expression of potential biomarkers in both benign and malignant pancreatic tumors was a major obstacle in the… 
Highly Cited
2007
Highly Cited
2007
Microfabricated two-dimensional electrophoresis device for differential protein expression profiling.
A microfluidic separation system is developed to perform two-dimensional differential gel electrophoretic (DIGE) separations of… 
Highly Cited
2006
Highly Cited
2006
Comparison of two proteomics techniques used to identify proteins regulated by gibberellin in rice.
Proteomics has become an essential methodology for large-scale analysis of proteins in various fields of plant biology. We… 
Highly Cited
2005
Highly Cited
2005
Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma
In order to identify new molecular markers for pancreatic intra‐epithelial neoplasias (PanINs), the precursor lesions of… 
Highly Cited
2004
Highly Cited
2004
DNA microarray normalization methods can remove bias from differential protein expression analysis of 2D difference gel electrophoresis results
MOTIVATION Two-dimensional Difference Gel Electrophoresis (DIGE) measures expression differences for thousands of proteins in… 
Highly Cited
2001
Highly Cited
2001
Fluorescent dual colour 2D-protein gel electrophoresis for rapid detection of differences in protein pattern with standard image analysis software.
The use of two different fluorescent dyes in two-dimensional (2D) polyacrylamide gel electrophoresis was recently described and… 
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